Evidence map›Paper›PMID 37176510›Full record

ArticleJournal of clinical medicine2023

Qualitative Assessment of Contrast-Enhanced Ultrasound in Differentiating Clear Cell Renal Cell Carcinoma and Oncocytoma.

Antonio Tufano, Costantino Leonardo, Chiara Di Bella, Giuseppe Lucarelli, Vincenzo Dolcetti, Piervito Dipinto, Flavia Proietti, Rocco Simone Flammia, Umberto Anceschi, Sisto Perdonà and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Antonio TufanoDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.
Costantino LeonardoDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.
Chiara Di BellaDepartment of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, 00162 Rome, Italy.
Giuseppe LucarelliDepartment of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, 00162 Rome, Italy.
Vincenzo DolcettiDepartment of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, 00162 Rome, Italy.
Piervito DipintoDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.
Flavia ProiettiDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.
Rocco Simone FlammiaDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.ORCID 0000-0002-3129-0544
Umberto AnceschiDepartment of Urology, IRCCS "Regina Elena" National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0002-7586-4132
Sisto PerdonàFondazione "G. Pascale" IRCCS, 80131 Naples, Italy.
Giorgio FrancoDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.
Alessandro SciarraDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.ORCID 0000-0002-7899-8056
Giovanni Battista Di PierroDepartment of Maternal-Child and Urological Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00162 Rome, Italy.ORCID 0000-0003-2321-0548
Vito CantisaniDepartment of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, 00162 Rome, Italy.
Policlinico Umberto I · ITSapienza University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to assess whether clear cell renal cell carcinoma (ccRCC) can be differentiated from renal oncocytoma (RO) on a contrast-enhanced ultrasound (CEUS).

methodsBetween January 2021 and October 2022, we retrospectively queried and analyzed our prospectively maintained dataset. Renal mass features were scrutinized with conventional ultrasound imaging (CUS) and CEUS. All lesions were confirmed by histopathologic diagnoses after nephron-sparing surgery (NSS). A multivariable analysis was performed to identify the potential predictors of ccRCC. The area under the curve (AUC) was depicted in order to assess the diagnostic accuracy of the multivariable model.

resultsA total of 126 renal masses, including 103 (81.7%) ccRCC and 23 (18.3%) RO, matched our inclusion criteria. Among these two groups, we found significant differences in terms of enhancement (homogeneous vs. heterogeneous) (

conclusionsDiagnostic imaging for presurgical planning is crucial in the choice of either conservative or radical management. CEUS, with its unique features, revealed its usefulness in differentiating ccRCC from RO.

Indexed as

accuracyCEUScontrast-enhanced ultrasoundkidney cancerkidney massesoncocytomarenal cancerrenal masses

Identifiers

PMID37176510
PMCPMC10179124
OpenAlexW4366828975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.