Evidence map›Paper›PMID 37176055›Full record

ArticleInternational journal of molecular sciences2023

Gene Expression Behavior of a Set of Genes in Platelet and Tissue Samples from Patients with Breast Cancer.

Luis A Burciaga-Hernandez, Cecilia F Cueto-Villalobos, Nancy Ortega-Piñon, Irma E Gonzalez-Curiel, Susana Godina-Gonzalez, Gwendolyne Mendez-Frausto, Anna P Aguilar-Esquivel, Vilma Maldonado-Lagunas, Luis E Guerrero-de la Torre, Jorge Melendez-Zajgla and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Luis A Burciaga-HernandezMaestría en Ciencias Biomédicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Cecilia F Cueto-VillalobosUnidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Nancy Ortega-PiñonUnidad Académica de Ciencias Biológicas, Universidad Autónoma de Zacatecas, Zacatecas 98068, Mexico.
Irma E Gonzalez-CurielLaboratorio de InmunotoxicologÍa y Terapéutica Experimental, Unidad Académica de Ciencias QuÍmicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0002-0044-9196
Susana Godina-GonzalezLaboratorio de Biomarcadores, Unidad Académica de Ciencias QuÍmicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0003-0340-9381
Gwendolyne Mendez-FraustoLaboratorio de InmunotoxicologÍa y Terapéutica Experimental, Unidad Académica de Ciencias QuÍmicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0001-9668-1127
Anna P Aguilar-EsquivelHospital General Zacatecas "Luz González Cosío", Zacatecas 98160, Mexico.
Vilma Maldonado-LagunasLaboratorio de Epigenetica, Instituto Nacional de Medicina Genomica (INMEGEN), Ciudad de México 14610, Mexico.ORCID 0000-0002-7254-5961
Luis E Guerrero-de la TorreMaestría en Ciencias Biomédicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Jorge Melendez-ZajglaLaboratorio de Genomica Funcional del Cancer, Instituto Nacional de Medicina Genomica (INMEGEN), Ciudad de México 14610, Mexico.ORCID 0000-0002-2209-1607
Erika K Sanchez-GarciaLaboratorio de Epigenetica, Instituto Nacional de Medicina Genomica (INMEGEN), Ciudad de México 14610, Mexico.ORCID 0000-0002-3277-2203
Irma B Mitre-AguilarUnidad de Bioquímica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran (INCMNSZ), Ciudad de México 14080, Mexico.ORCID 0000-0001-6955-9003
Gretel Mendoza-AlmanzaMaestría en Ciencias Biomédicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0002-0426-7410
Universidad Autónoma de Zacatecas "Francisco García Salinas" · MXNational Institute of Genomic Medicine · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MX

Funding

Consejo Nacional de Ciencia y Tecnología 6368
6 · The paper itself

Abstract

The tumor microenvironment (TME) is constituted by a great diversity of highly dynamic cell populations, each of which contributes ligands, receptors, soluble proteins, mRNAs, and miRNAs, in order to regulate cellular activities within the TME and even promote processes such as angiogenesis or metastasis. Intravasated platelets (PLT) undergo changes in the TME that convert them into tumor-educated platelets (TEP), which supports the development of cancer, angiogenesis, and metastasis through the degranulation and release of biomolecules. Several authors have reported that the deregulation of

Indexed as

Breast NeoplasmsMicroRNAsBlood PlateletsFemaleGene ExpressionHumansMembrane ProteinsOncogene ProteinsRNA, MessengerTumor MicroenvironmentWiskott-Aldrich Syndrome Protein FamilyLAPTM4B protein, humanMembrane ProteinsMicroRNAsOncogene ProteinsRNA, MessengerWASF3 protein, humanWiskott-Aldrich Syndrome Protein Familybiomarkers panelbreast cancergene overexpressiontumor-educated plateletsvariation in mRNA levels

Identifiers

PMID37176055
PMCPMC10179257
OpenAlexW4376631219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.