Evidence map›Paper›PMID 37176022›Full record

ArticleInternational journal of molecular sciences2023

Efficacy of a Multicomponent Nutraceutical Formulation for the Prevention and Treatment of Urinary Tract Stones.

Maria Maisto, Elisabetta Schiano, Gianni Luccheo, Luigi Luccheo, Ernesto Alfieri, Vincenzo Piccolo, Fortuna Iannuzzo, Ritamaria Di Lorenzo, Gian Carlo Tenore

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Efficacy and Safety of Boldine Combined withMedicina (Kaunas, Lithuania) · 2024
    Article
  2. International journal of molecular sciences · 2024
    Review
  3. Oxalates: Dietary Oxalates and Kidney Inflammation: A Literature Review.Integrative medicine (Encinitas, Calif.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria MaistoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-0340-2254
Elisabetta SchianoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-8167-0334
Gianni LuccheoNutriphyt Lab, Anvest Health s.r.l., Via Gabriele Camozzi 12, 20152 Milan, Italy.
Luigi LuccheoNutriphyt Lab, Anvest Health s.r.l., Via Gabriele Camozzi 12, 20152 Milan, Italy.
Ernesto AlfieriNutriphyt Lab, Anvest Health s.r.l., Via Gabriele Camozzi 12, 20152 Milan, Italy.
Vincenzo PiccoloDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0003-4480-5022
Fortuna IannuzzoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0001-6340-6698
Ritamaria Di LorenzoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0003-1406-6214
Gian Carlo TenoreDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 59, 80131 Naples, Italy.ORCID 0000-0002-0251-9936

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urolithiasis is a complex and multifactorial disease characterized by the formation of calculi at the urinary tract level. Conventional therapeutic prophylaxis relies on the use of Ca-blockers, alkalis, diuretics, and anti-edema agents, but their prolonged utilization is often limited by several side effects. In this scenario, the aim of the present work was the design of an innovative multi-component nutraceutical formulation (NF) for the management of urinary stones consisting of a synergistic combination of natural aqueous extracts of

Indexed as

Kidney CalculiUrinary CalculiUrolithiasisAnimalsCalcium OxalateDietary SupplementsHumansRatsCalcium Oxalateanti-edema activitycalcium-oxalate crystalmyorelaxant effectnutraceutical formulationuric acid cellular transportersurinary tract stones

Identifiers

PMID37176022
PMCPMC10178978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.