Evidence map›Paper›PMID 37176019›Full record

ReviewInternational journal of molecular sciences2023

Recent Advances in Characterization of Melanin Pigments in Biological Samples.

Kazumasa Wakamatsu, Shosuke Ito

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Toxicological Assessment and Dual Protective Roles ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Dismantling darkness: interdisciplinary perspectives on melanin degradation.World journal of microbiology & biotechnology · 2026
    Review
  9. Review
  10. AlkylAntioxidants (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
  13. From melanogenesis to melanin technologies.Communications chemistry · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kazumasa WakamatsuInstitute for Melanin Chemistry, Fujita Health University, Toyoake 470-192, Aichi, Japan.ORCID 0000-0003-1748-9001
Shosuke ItoInstitute for Melanin Chemistry, Fujita Health University, Toyoake 470-192, Aichi, Japan.ORCID 0000-0001-9182-5144
Fujita Health University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The melanin pigments eumelanin (EM) and pheomelanin (PM), which are dark brown to black and yellow to reddish-brown, respectively, are widely found among vertebrates. They are produced in melanocytes in the epidermis, hair follicles, the choroid, the iris, the inner ear, and other tissues. The diversity of colors in animals is mainly caused by the quantity and quality of their melanin, such as by the ratios of EM versus PM. We have developed micro-analytical methods to simultaneously measure EM and PM and used these to study the biochemical and genetic fundamentals of pigmentation. The photoreactivity of melanin has become a major focus of research because of the postulated relevance of EM and PM for the risk of UVA-induced melanoma. Our biochemical methods have found application in many clinical studies on genetic conditions associated with alterations in pigmentation. Recently, besides chemical degradative methods, other methods have been developed for the characterization of melanin, and these are also discussed here.

Indexed as

MelaninsMelanomaAnimalsEpidermisMelanocytesPigmentationMelaninsalkaline hydrogen peroxide oxidation (AHPO)electron paramagnetic resonance spectroscopyeumelaninhydroiodic acid hydrolysisLC–MSpheomelaninpump–probe microscopyRaman spectroscopytape stripping

Identifiers

PMID37176019
PMCPMC10179066
OpenAlexW4376630058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.