Evidence map›Paper›PMID 37175986›Full record

ArticleInternational journal of molecular sciences2023

Design, Synthesis, and Anti-PVY Biological Activity of 1,3,5-Triazine Derivatives Containing Piperazine Structure.

Lian Bai, Chunle Wei, Jian Zhang, Runjiang Song

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lian BaiCenter for R&D of Fine Chemicals of Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, National Key Laboratory of Green Pesticide, Guiyang 550025, China.ORCID 0000-0003-3682-9411
Chunle WeiCenter for R&D of Fine Chemicals of Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, National Key Laboratory of Green Pesticide, Guiyang 550025, China.ORCID 0000-0003-3288-0332
Jian ZhangCenter for R&D of Fine Chemicals of Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, National Key Laboratory of Green Pesticide, Guiyang 550025, China.
Runjiang SongCenter for R&D of Fine Chemicals of Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, National Key Laboratory of Green Pesticide, Guiyang 550025, China.ORCID 0000-0003-2502-778X

Funding

Wellcome Trust 202231
6 · The paper itself

Abstract

In this study, a commercial agent with antivirus activity and moroxydine hydrochloride were employed to perform a lead optimization. A series of 1,3,5-triazine derivatives with piperazine structures were devised and synthesized, and an evaluation of their anti-potato virus Y (PVY) activity revealed that several of the target compounds possessed potent anti-PVY activity. The synthesis of compound

Indexed as

PotyvirusTobacco Mosaic VirusAntiviral AgentsBiguanidesMolecular Docking SimulationMorpholinesPiperazineTriazinesAntiviral AgentsBiguanidesmoroxydineMorpholinesPiperazineTriazines1,3,5-triazine derivatives3D-QSARpiperazinepotato virus Y

Identifiers

PMID37175986
PMCPMC10179359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.