Evidence map›Paper›PMID 37175941›Full record

ArticleInternational journal of molecular sciences2023

Analysis of Radiation Toxicity in Mammalian Cells Stably Transduced with Mitochondrial

Alisa Zanin, Giacomo Meneghetti, Luca Menilli, Annachiara Tesoriere, Francesco Argenton, Maddalena Mognato

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alisa ZaninDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35131 Padova, Italy.
Giacomo MeneghettiDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35131 Padova, Italy.
Luca MenilliDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35131 Padova, Italy.ORCID 0000-0003-2774-6411
Annachiara TesoriereDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35131 Padova, Italy.
Francesco ArgentonDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35131 Padova, Italy.ORCID 0000-0002-0803-8236
Maddalena MognatoDepartment of Biology, University of Padova, Via U. Bassi 58/B, 35131 Padova, Italy.ORCID 0000-0001-6132-1682
University of Padua · IT

Funding

Associazione Italiana per la Ricerca sul Cancro (AIRC) IG 2017 19928 to F.A.University of Padova BIRD-SEED 2021 to M.M.
6 · The paper itself

Abstract

A coordinated action between nuclear and mitochondrial activities is essential for a proper cellular response to genotoxic stress. Several nuclear transcription factors, including STAT3, translocate to mitochondria to exert mitochondrial function regulation; however, the role of mitochondrial STAT3 (mitoSTAT3) under stressed conditions is still poorly understood. In this study, we examined whether the stable expression of mitoSTAT3 wild-type or mutated at the conserved serine residue (Ser727), which is involved in the mitochondrial function of STAT3, can affect the DNA damage response to UVC radiation. To address this issue, we generated mammalian cells (NIH-3T3 and HCT-116 cells) stably transduced to express the mitochondrial-targeted

Indexed as

MitochondriaOxidative StressAnimalsCell ProliferationMammalsMiceSerineSTAT3 Transcription FactorSerineSTAT3 Transcription Factorcell deathcell survivalgenotoxic stressmitochondrial STAT3UVC radiation

Identifiers

PMID37175941
PMCPMC10179518
OpenAlexW4376629919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.