Evidence map›Paper›PMID 37175887›Full record

ArticleInternational journal of molecular sciences2023

ABCA3 Deficiency-Variant-Specific Response to Hydroxychloroquine.

Xiaohua Yang, Maria Forstner, Christina K Rapp, Ina Rothenaigner, Yang Li, Kamyar Hadian, Matthias Griese

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Old and emerging therapies for childhood interstitial lung disease (chILD): a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Review
  3. Article
  4. Genetic susceptibility to interstitial lung disease: a case ofQuantitative imaging in medicine and surgery · 2025
    Article
  5. Article
  6. Respirology case reports · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xiaohua YangDr. von Haunersches Kinderspital, German Center for Lung Research, University of Munich, Lindwurmstr. 4a, 80337 Munich, Germany.
Maria ForstnerDr. von Haunersches Kinderspital, German Center for Lung Research, University of Munich, Lindwurmstr. 4a, 80337 Munich, Germany.
Christina K RappDr. von Haunersches Kinderspital, German Center for Lung Research, University of Munich, Lindwurmstr. 4a, 80337 Munich, Germany.ORCID 0000-0002-7371-8158
Ina RothenaignerResearch Unit Signaling and Translation, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
Yang LiDr. von Haunersches Kinderspital, German Center for Lung Research, University of Munich, Lindwurmstr. 4a, 80337 Munich, Germany.
Kamyar HadianResearch Unit Signaling and Translation, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
Matthias GrieseDr. von Haunersches Kinderspital, German Center for Lung Research, University of Munich, Lindwurmstr. 4a, 80337 Munich, Germany.ORCID 0000-0003-0113-912X
German Center for Lung Research · DEHelmholtz Zentrum München · DE

Funding

Deutsche Forschungsgemeinschaft DFG Gr 970/9-2
6 · The paper itself

Abstract

Biallelic variants in

Indexed as

HydroxychloroquineLung Diseases, InterstitialATP-Binding Cassette TransportersChildHumansLungMutationRetrospective StudiesABCA3 protein, humanATP-Binding Cassette TransportersHydroxychloroquineABCA3ATP-binding cassette subfamily A member 3chILDchildhood interstitial lung diseasediffuse parenchymal lung diseaseHCQhydroxychloroquineILDinterstitial lung disease

Identifiers

PMID37175887
PMCPMC10179277
OpenAlexW4376630655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.