ArticleInternational journal of molecular sciences2023
A New Unified Theory of Trigger Point Formation: Failure of Pre- and Post-Synaptic Feedback Control Mechanisms.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Clinical effects of passive cable theory applied via subthreshold electrical stimulation in chronic neck pain: A randomized trial.PM & R : the journal of injury, function, and rehabilitation · 2026Trial
- Ultrasonographic identification of pelvic floor myofascial trigger points and their correlation with clinical symptoms in patients with pelvic floor myofascial pain.Quantitative imaging in medicine and surgery · 2026Article
- Prevalence and Predictive Factors of Active Myofascial Trigger Points Among Office Workers Using to Visual Display Terminals: A Cross-Sectional Study.Archives of rehabilitation research and clinical translation · 2026Article
- Pain Unraveled: Kinesio Taping as a Novel Approach to Myofascial Pain Management.Current pain and headache reports · 2026Review
- Microdialysis Evaluation of Blood Flow, Lactate, and Glucose in Active Trigger Points of Tension-Type Headache Patients and Latent Trigger Points in Healthy Muscle.Archives of physical medicine and rehabilitation · 2026Observational
- The protective model of myofascial trigger points: a testable systems-level framework based on strain-repair mismatch.Frontiers in physiology · 2026Article
- Myofascial trigger points as a primary cause of equine lameness: a biomechanical, neurophysiological, and fascial review.Frontiers in veterinary science · 2026Review
- Inhibition of the AMPK/PGC-1α/Mfn2 Axis is Associated with Mitochondria-ER Dysfunction and Ultrastructural Remodeling in a Rat Model of Myofascial Trigger Points.Journal of pain research · 2026Article
- Reframing myofascial pain syndrome: pathological disorder or adaptive protective response?Therapeutic advances in musculoskeletal disease · 2026Review
- Clinical Effectiveness of Dry Needling on Myofascial Trigger Points in Horses: A Prospective Algometric Controlled Study.Animals : an open access journal from MDPI · 2025Article
- Prevalence and location of myofascial trigger points in dogs with osteoarthritis.Frontiers in veterinary science · 2025Article
- Bio-tensegrity and extracellular matrix disruption in the pathogenesis of persistent post-operative pain: a hypothesis.Frontiers in physiology · 2025Article
- Effects of platelet-rich plasma injection on electrical activity and biomechanics of the erector spinae muscles in lumbar myofascial pain syndrome.Scientific reports · 2024Article
- Prevalence of Myofascial Trigger Points in Isolated Idiopathic Cervical Dystonia: A Possible Contributor to Pain, Movement and Disability.Movement disorders clinical practice · 2024Article
- Research Progress on the Experimental Model and Underlying Mechanistic Studies of Tension-Type Headaches.Current pain and headache reports · 2024Review
- Modeling of the Effect of Subperiosteal Hydrostatic Pressure Conductivity between Joints on Decreasing Contact Loads on Cartilage and of the Effect of Myofascial Relief in Treating Trigger Points: The Floating Skeleton Theory.Biomimetics (Basel, Switzerland) · 2024Article
- Myofascial trigger point (MTrP) size and elasticity properties can be used to differentiate characteristics of MTrPs in lower back skeletal muscle.Scientific reports · 2024Article
- Effect of transcutaneous neuromodulation on normalization of dermal body temperature and pain in a tender scar in the presence of low back pain: An update and case report.SAGE open medical case reports · 2024Article
- Advancing musculoskeletal diagnosis and therapy: a comprehensive review of trigger point theory and muscle pain patterns.Frontiers in medicine · 2024Article
- Summaries of the Padua symposium on myofascial pain, fibromyalgia, and fascial pain disorders, June 2023,European journal of translational myology · 2023Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The origin of the myofascial trigger point (TrP), an anomalous locus in muscle, has never been well-described. A new trigger point hypothesis (the new hypothesis) presented here addresses this lack. The new hypothesis is based on the concept that existing myoprotective feedback mechanisms that respond to muscle overactivity, low levels of adenosine triphosphate, (ATP) or a low pH, fail to protect muscle in certain circumstances, such as intense muscle activity, resulting in an abnormal accumulation of intracellular Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.