Evidence map›Paper›PMID 37175820›Full record

ArticleInternational journal of molecular sciences2023

Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling.

Xinglian Xu, Lulu Deng, Yaling Tang, Jiang Li, Ting Zhong, Xiaojiang Hao, Yanhua Fan, Shuzhen Mu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xinglian XuState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.
Lulu DengState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.
Yaling TangThe Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, 3491 Beijin Road, Guiyang 550014, China.
Jiang LiState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.
Ting ZhongState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.
Xiaojiang HaoState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.
Yanhua FanState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.
Shuzhen MuState Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Beijin Road, Guiyang 550014, China.
Guiyang Medical University · CNKey Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences · CNChinese Academy of Sciences · CNKunming Institute of Botany · CN

Funding

National Natural Science Foundation of China 22067003National Natural Science Foundation of China 31760097National Natural Science Foundation of China U1812403-3Science and Technology Program of Guizhou Province (QKH-JC [2019]1430)Science and Technology Projects of GuizhouProvince (QKH Foundation-ZK (2021) General 516)Technological Talents in Colleges and Universities of Guizhou Province (Qian Ke He KY (2021) 181)
6 · The paper itself

Abstract

Sanguinarine (

Indexed as

Cytostatic AgentsLeukemiaLeukemia, Erythroblastic, AcuteApoptosisBenzophenanthridinesCell Line, TumorCyanidesHumansIsoquinolinesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktBenzophenanthridinesCyanidesCytostatic AgentsIsoquinolinesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktsanguinarinec-METleukemiaMAPKPI3K/mTORsanguinarineSTAT3

Identifiers

PMID37175820
PMCPMC10179035
OpenAlexW4367628113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.