Evidence map›Paper›PMID 37175786›Full record

ArticleInternational journal of molecular sciences2023

Multiplex Lithographic SERS Aptasensor for Detection of Several Respiratory Viruses in One Pot.

Vladimir Kukushkin, Oganes Ambartsumyan, Alexei Subekin, Anna Astrakhantseva, Vladimir Gushchin, Alexandra Nikonova, Anastasia Dorofeeva, Vitaly Zverev, Anna Keshek, Nadezda Meshcheryakova and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. COVID-19 Pandemic: Therapeutic Strategies and Vaccines.International journal of molecular sciences · 2023
    Article
  8. Article
  9. Rapid SERS Detection of Botulinum Neurotoxin Type A.Nanomaterials (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Vladimir KukushkinOsipyan Institute of Solid State Physics, Russian Academy of Science, 142432 Chernogolovka, Russia.ORCID 0000-0001-6731-9508
Oganes AmbartsumyanMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Alexei SubekinMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Anna AstrakhantsevaOsipyan Institute of Solid State Physics, Russian Academy of Science, 142432 Chernogolovka, Russia.
Vladimir GushchinN. F. Gamaleya Federal Research Center for Epidemiology & Microbiology, 123098 Moscow, Russia.ORCID 0000-0002-9397-3762
Alexandra NikonovaMechnikov Research Institute of Vaccines and Sera, 105064 Moscow, Russia.
Anastasia DorofeevaMechnikov Research Institute of Vaccines and Sera, 105064 Moscow, Russia.
Vitaly ZverevMechnikov Research Institute of Vaccines and Sera, 105064 Moscow, Russia.
Anna KeshekChemistry Department of Lomonosov, Moscow State University, 119991 Moscow, Russia.
Nadezda MeshcheryakovaChemistry Department of Lomonosov, Moscow State University, 119991 Moscow, Russia.
Olga ZaborovaChemistry Department of Lomonosov, Moscow State University, 119991 Moscow, Russia.
Alexandra GambaryanChumakov Federal Scientific Center for Research, Development of Immune and Biological Products RAS, 108819 Moscow, Russia.ORCID 0000-0002-1892-0548
Elena ZavyalovaChemistry Department of Lomonosov, Moscow State University, 119991 Moscow, Russia.ORCID 0000-0001-5260-1973
Lomonosov Moscow State University · RUMoscow Institute of Physics and Technology · RUResearch Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences · RUGamalei Institute of Epidemiology and Microbiology · RUOsipyan Institute of Solid State Physics RAS · RU

Funding

Russian Science Foundation [# 18-74-10019, https://rscf.ru/project/18-74-10019
6 · The paper itself

Abstract

Rapid and reliable techniques for virus identification are required in light of recurring epidemics and pandemics throughout the world. Several techniques have been distributed for testing the flow of patients. Polymerase chain reaction with reverse transcription is a reliable and sensitive, though not rapid, tool. The antibody-based strip is a rapid, though not reliable, and sensitive tool. A set of alternative tools is being developed to meet all the needs of the customer. Surface-enhanced Raman spectroscopy (SERS) provides the possibility of single molecule detection taking several minutes. Here, a multiplex lithographic SERS aptasensor was developed aiming at the detection of several respiratory viruses in one pot within 17 min. The four labeled aptamers were anchored onto the metal surface of four SERS zones; the caught viruses affect the SERS signals of the labels, providing changes in the analytical signals. The sensor was able to decode mixes of SARS-CoV-2 (severe acute respiratory syndrome coronavirus two), influenza A virus, respiratory syncytial virus, and adenovirus within a single experiment through a one-stage recognition process.

Indexed as

Biosensing TechniquesCOVID-19HumansOligonucleotidesRespiratory Syncytial VirusesSARS-CoV-2Spectrum Analysis, RamanOligonucleotidesadenovirusaptameraptasensorinfluenza virusrespiratory syncytial virusSARS-CoV-2sensorSERSvirus

Identifiers

PMID37175786
PMCPMC10178974
OpenAlexW4367626220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.