Evidence map›Paper›PMID 37175660›Full record

ArticleInternational journal of molecular sciences2023

The Functional Role and Regulatory Mechanism of FTO m

Qiwei Yang, Ayman Al-Hendy

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Emerging roles of RNA mInternational journal of oncology · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  10. Regulation and application of mScience China. Life sciences · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. The mFrontiers in pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Qiwei YangDepartment of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-7131-8946
Ayman Al-HendyDepartment of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-8778-4447
University of Chicago · US

Funding

Training the Trainers: Building Institutional Data Science Capacity to Support Health Disparities ResearchU54MD007602 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI Kevin Sean Kimbro · 2018 to 2026
$47.6M
Investigating the effectiveness of COVID-19 testing choices, community engagement, and culturally-embedded mHealth literacy delivery in a medically-underserved, community-based sampleR01ES028615 · NIEHS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AL-HENDY, AYMAN, WALKER, CHERYL L. · 2017 to 2022
$5.0M
Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroidsR01HD094378 · NICHD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI AL-HENDY, AYMAN, BOYER, THOMAS G · 2018 to 2022
$4.2M
Mechanisms of actions(s) of simvastatin in uterine leiomyomaR01HD094380 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BORAHAY, MOSTAFA A. · 2018 to 2022
$4.0M
Pathological reprogramming of the m6A epitranscriptome in uterine fibroidsR01HD106285 · NICHD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI AL-HENDY, AYMAN, BOYER, THOMAS G · 2021 to 2025
$3.2M
NICHD NIH HHS R01 HD094378NICHD NIH HHS R01 HD094380NICHD NIH HHS R01 HD106285NIEHS NIH HHS R01 ES028615NIMHD NIH HHS U54 MD007602
6 · The paper itself

Abstract

Uterine leiomyosarcoma (uLMS) is the most frequent subtype of uterine sarcoma that presents a poor prognosis and high rates of recurrence and metastasis. The origin and molecular mechanism underlying and driving its clinical and biological behavior remain largely unknown. Recently, we and others have revealed the role of microRNAs, DNA methylation, and histone modifications in contributing to the pathogenesis of uLMS. However, the connection between reversible m

Indexed as

LeiomyosarcomaMicroRNAsPelvic NeoplasmsUterine NeoplasmsAlpha-Ketoglutarate-Dependent Dioxygenase FTOFemaleHumansProto-Oncogene Proteins c-mycSignal TransductionAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanMicroRNAsProto-Oncogene Proteins c-mycapoptosiscell cycleDAC51demethylasehistone modificationsmiRNAsRNA methylationtranscription factorstranscriptome analysisuterine leiomyosarcoma

Identifiers

PMID37175660
PMCPMC10178470
OpenAlexW4367299731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.