Evidence map›Paper›PMID 37175515›Full record

ReviewInternational journal of molecular sciences2023

APP in the Neuromuscular Junction for the Development of Sarcopenia and Alzheimer's Disease.

Min-Yi Wu, Wen-Jun Zou, Daehoon Lee, Lin Mei, Wen-Cheng Xiong

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Body Composition and Alzheimer's Disease: A Holistic Review.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Min-Yi WuDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Wen-Jun ZouDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Daehoon LeeDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Lin MeiDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
Wen-Cheng XiongDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.ORCID 0000-0001-9071-7598
Case Western Reserve University · USVA Northeast Ohio Healthcare System · US

Funding

Swedish APP mutation and NMJ decline in Alzheimer's diseaseRF1AG051510 · NIA · CASE WESTERN RESERVE UNIVERSITY · PI XIONG, WEN-CHENG, ZIGMOND, RICHARD E · 2020 to 2020
$2.6M
Swedish APP mutation and NMJ decline in Alzheimer's diseaseR01AG051510 · NIA · CASE WESTERN RESERVE UNIVERSITY · PI XIONG, WEN-CHENG, ZIGMOND, RICHARD E · 2015 to 2024
$2.6M
Skeletal Muscular Swedish Mutant APP in Alzheimer's Disease DevelopmentI01BX005642 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI XIONG, WEN-CHENG · 2022 to 2025
–
BLRD VA I01 BX005642NIA NIH HHS R01 AG051510NIA NIH HHS RF1 AG051510
6 · The paper itself

Abstract

Sarcopenia, an illness condition usually characterized by a loss of skeletal muscle mass and muscle strength or function, is often associated with neurodegenerative diseases, such as Alzheimer's disease (AD), a common type of dementia, leading to memory loss and other cognitive impairment. However, the underlying mechanisms for their associations and relationships are less well understood. The

Indexed as

Alzheimer DiseaseSarcopeniaAmyloid beta-PeptidesAmyloid beta-Protein PrecursorHumansNeuromuscular JunctionSynapsesAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAPP protein, humanAlzheimer’s diseaseamyloid precursor proteinneurodegenerative diseasesneuromuscular junctionsarcopenia

Identifiers

PMID37175515
PMCPMC10178513
OpenAlexW4366991132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.