Evidence map›Paper›PMID 37175478›Full record

ArticleInternational journal of molecular sciences2023

Acute Downregulation but Not Genetic Ablation of Murine MCU Impairs Suppressive Capacity of Regulatory CD4 T Cells.

Priska Jost, Franziska Klein, Benjamin Brand, Vanessa Wahl, Amanda Wyatt, Daniela Yildiz, Ulrich Boehm, Barbara A Niemeyer, Martin Vaeth, Dalia Alansary

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Priska JostMolecular Biophysics, Saarland University, 66421 Homburg, Germany.
Franziska KleinMolecular Biophysics, Saarland University, 66421 Homburg, Germany.
Benjamin BrandWürzburg Institute of Systems Immunology, Max Planck Research Group at Julius-Maximilians University of Würzburg, 97078 Würzburg, Germany.
Vanessa WahlExperimental Pharmacology, Center for Molecular Signaling (PZMS), School of Medicine, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-0070-3465
Amanda WyattExperimental Pharmacology, Center for Molecular Signaling (PZMS), School of Medicine, Saarland University, 66421 Homburg, Germany.ORCID 0000-0003-1107-3857
Daniela YildizExperimental Pharmacology, Center for Molecular Signaling (PZMS), School of Medicine, Saarland University, 66421 Homburg, Germany.
Ulrich BoehmExperimental Pharmacology, Center for Molecular Signaling (PZMS), School of Medicine, Saarland University, 66421 Homburg, Germany.
Barbara A NiemeyerMolecular Biophysics, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-6963-0575
Martin VaethWürzburg Institute of Systems Immunology, Max Planck Research Group at Julius-Maximilians University of Würzburg, 97078 Würzburg, Germany.
Dalia AlansaryMolecular Biophysics, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-7541-6057
Saarland University · DEUniversity of Würzburg · DE

Funding

Saarland University, DFG 322900939
6 · The paper itself

Abstract

By virtue of mitochondrial control of energy production, reactive oxygen species (ROS) generation, and maintenance of Ca

Indexed as

Calcium ChannelsT-Lymphocytes, RegulatoryAnimalsCalciumCD4-Positive T-LymphocytesDown-RegulationMiceMitochondriaMitochondrial ProteinsCalciumCalcium ChannelsMcu protein, mouseMitochondrial Proteinsmitochondrial calcium uniporterregulatory T cellssuppressive capacity

Identifiers

PMID37175478
PMCPMC10178810
OpenAlexW4366988989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.