Evidence map›Paper›PMID 37175474›Full record

ArticleInternational journal of molecular sciences2023

Exploring the Binding of Natural Compounds to Cancer-Related G-Quadruplex Structures: From 9,10-Dihydrophenanthrenes to Their Dimeric and Glucoside Derivatives.

Chiara Platella, Andrea Criscuolo, Claudia Riccardi, Rosa Gaglione, Angela Arciello, Domenica Musumeci, Marina DellaGreca, Daniela Montesarchio

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chiara PlatellaDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0002-6997-1767
Andrea CriscuoloDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0003-3105-7758
Claudia RiccardiDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0002-7182-0757
Rosa GaglioneDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0003-2391-0237
Angela ArcielloDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.
Domenica MusumeciDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0001-7624-1933
Marina DellaGrecaDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0001-6530-605X
Daniela MontesarchioDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy.ORCID 0000-0001-6295-6911

Funding

Italian Association for Cancer Research AIRC IG2020 n. 25046 to D. Montesarchio
6 · The paper itself

Abstract

In-depth studies on the interaction of natural compounds with cancer-related G-quadruplex structures have been undertaken only recently, despite their high potential as anticancer agents, especially due to their well-known and various bioactivities. In this frame, aiming at expanding the repertoire of natural compounds able to selectively recognize G-quadruplexes, and particularly focusing on phenanthrenoids, a mini-library including dimeric (

Indexed as

Antineoplastic AgentsG-QuadruplexesNeoplasmsGlucosidesHumansLigandsMolecular Docking SimulationTelomereAntineoplastic AgentsGlucosidesLigandscancerdihydrophenanthrenoidsglucosidesG-quadruplexnatural compounds

Identifiers

PMID37175474
PMCPMC10178421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.