Evidence map›Paper›PMID 37175425›Full record

ArticleInternational journal of molecular sciences2023

The Anti-Atopic Dermatitis Effects of

So-Yeon Kim, Arjun Sapkota, Young Joo Bae, Seung-Hyuk Choi, Ho Jung Bae, Hyun-Jeong Kim, Ye Eun Cho, Yu-Yeong Choi, Ju-Yeon An, So-Young Cho and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Investigating the Health Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Review
  7. Special Issue "Molecular and Cellular Advances in Atopic Diseases".International journal of molecular sciences · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

So-Yeon KimDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.ORCID 0000-0003-1885-0540
Arjun SapkotaCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Republic of Korea.
Young Joo BaeCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Republic of Korea.
Seung-Hyuk ChoiDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Ho Jung BaeAgriculture and Life Science Research Institute, Kangwon National University, Chuncheon 24341, Republic of Korea.
Hyun-Jeong KimDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Ye Eun ChoDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Yu-Yeong ChoiDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Ju-Yeon AnDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
So-Young ChoDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.
Sun Hee HongSchool of Applied Science in Natural Resources & Environment, Hankyong National University, Anseong 17579, Republic of Korea.ORCID 0000-0001-7581-0604
Ji Woong ChoiCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Republic of Korea.
Se Jin ParkDepartment of Food Biotechnology and Environmental Science, Kangwon National University, Chuncheon 24341, Republic of Korea.ORCID 0000-0002-9370-5258
Kangwon National University · KRGachon University · KRHankyong National University · KR

Funding

Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education NRF-2021R1A6A1A03044242Korean Ministry of Environment 2018002270002
6 · The paper itself

Abstract

The NLRP3 inflammasome is upregulated by various agents, such as nuclear factor-kappa B (NF-κB), lipopolysaccharide (LPS), and adenosine triphosphate (ATP). The NLRP3 inflammasome facilitations the maturation of interleukin (IL)-1β, a proinflammatory cytokine that is critically involved in the pathogenesis of atopic dermatitis (AD). Although the NLRP3 inflammasome clearly exacerbates AD symptoms such as erythema and pruritus, drugs for AD patients targeting the NLRP3 inflammasome are still lacking. Based on the previous findings that

Indexed as

Dermatitis, AtopicInflammasomesAnimalsCytokinesDinitrochlorobenzeneDisease Models, AnimalLipopolysaccharidesMiceMice, Inbred BALB CNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinCytokinesDinitrochlorobenzeneInflammasomesLipopolysaccharidesNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseatopic dermatitisBMDMsIL-1βMentha arvensisNLRP3 inflammasome

Identifiers

PMID37175425
PMCPMC10177797
OpenAlexW4366829202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.