ArticleMolecules (Basel, Switzerland)2023
β-Carboline-α-aminophosphonate Derivative: A Promising Antitumor Agent for Breast Cancer Treatment.
Caroline Pinto Zani, Aline Pinto Zani, Cristiane Melissa Thomazini, Karina Miyuki Retamiro, Aline Rufino de Oliveira, Débora Laís Gonçalves, Maria Helena Sarragiotto, Francielle Pelegrin Garcia, Sueli de Oliveira Silva, Celso Vataru Nakamura and 1 more
Open access · goldAbstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 8 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors at 1 institution in 1 country.
Caroline Pinto ZaniLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.
Aline Pinto ZaniLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.
Cristiane Melissa ThomaziniLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.
Karina Miyuki RetamiroLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.
Aline Rufino de OliveiraDepartment of Chemistry, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.
Débora Laís GonçalvesDepartment of Chemistry, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.
Maria Helena SarragiottoDepartment of Chemistry, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.
Francielle Pelegrin GarciaLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.ORCID 0000-0001-8966-9154 Sueli de Oliveira SilvaLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.ORCID 0000-0001-9303-0804 Celso Vataru NakamuraLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.ORCID 0000-0002-9911-7369 Tania Ueda-NakamuraLaboratory of Technological Innovation in the Development of Pharmaceuticals and Cosmetics, State University of Maringá, Maringá CEP 87020-900, Paraná, Brazil.ORCID 0000-0001-5057-3518 Universidade Estadual de Maringá · BR
Funding
National Council for Scientific and Technological Development 421944/2018-8
6 · The paper itselfAbstract
Breast cancer is the most common type of cancer and the leading cause of cancer mortality among women worldwide. Considering the limitations of the current treatments available, we analyzed the in vitro cytotoxic potential of ((4-Fluoro-phenyl)-{2-[(1-phenyl-9H-β-carboline-3-carbonyl)-amino]-ethylamino}-methyl)-phosphonic acid dibutyl ester (
Indexed as
Antineoplastic AgentsBreast NeoplasmsApoptosisApoptosis Regulatory ProteinsCarbolinesCell Cycle CheckpointsCell Line, TumorCell ProliferationFemaleHumansMCF-7 CellsAntineoplastic AgentsApoptosis Regulatory ProteinsCarbolinesapoptosisautophagybreast cancerMCF-7MDA-MB-231
Identifiers
PMID37175359
PMCPMC10179861
OpenAlexW4375863326
What OpenQuestion holds
Textmetadata
LicenceCC BY
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