Evidence map›Paper›PMID 37175322›Full record

ArticleMolecules (Basel, Switzerland)2023

Novel Pyrimidine Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Molecular Modeling Studies.

Malama Myriagkou, Evangelia Papakonstantinou, Georgia-Eirini Deligiannidou, Alexandros Patsilinakos, Christos Kontogiorgis, Eleni Pontiki

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Diverse Biological Activity of Pyrimidine Derivatives: A Review.Current drug discovery technologies · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Advances in the Synthesis and SAR of Pyrido[2,3-Current pharmaceutical design · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. DistinctFrontiers in microbiomes · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Malama MyriagkouDepartment of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Evangelia PapakonstantinouLaboratory of Hygiene and Environmental Protection, School of Medicine, Democritus University of Thrace, 25510 Alexandroupoli, Greece.
Georgia-Eirini DeligiannidouLaboratory of Hygiene and Environmental Protection, School of Medicine, Democritus University of Thrace, 25510 Alexandroupoli, Greece.ORCID 0000-0003-3976-4473
Alexandros PatsilinakosDepartment of Drug Chemistry and Technology, Sapienza University, 00185 Rome, Italy.ORCID 0000-0001-5961-3328
Christos KontogiorgisLaboratory of Hygiene and Environmental Protection, School of Medicine, Democritus University of Thrace, 25510 Alexandroupoli, Greece.ORCID 0000-0001-7835-8246
Eleni PontikiDepartment of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-0099-5653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heterocyclic ring system of pyrido [2,3-

Indexed as

Antineoplastic AgentsAntioxidantsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorGlutathioneMolecular Docking SimulationMolecular StructurePyrimidinesStructure-Activity RelationshipAntineoplastic AgentsAntioxidantsGlutathionePyrimidinesanti-inflammatoryantioxidantcytotoxicityHaCaTLOX inhibitionpyrimidine derivatives

Identifiers

PMID37175322
PMCPMC10180197

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.