Evidence map›Paper›PMID 37175309›Full record

ArticleMolecules (Basel, Switzerland)2023

Novel Derivatives of Eugenol as a New Class of PPARγ Agonists in Treating Inflammation: Design, Synthesis, SAR Analysis and In Vitro Anti-Inflammatory Activity.

Noor Fathima Anjum, Dhivya Shanmugarajan, B R Prashantha Kumar, Syed Faizan, Priya Durai, Ruby Mariam Raju, Saleem Javid, Madhusudan N Purohit

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Noor Fathima AnjumDepartment of Pharmaceutical Chemistry, Farooqia College of Pharmacy, Mysuru 570 015, India.
Dhivya ShanmugarajanDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570 015, India.
B R Prashantha KumarDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570 015, India.
Syed FaizanDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570 015, India.ORCID 0000-0001-6104-0557
Priya DuraiDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570 015, India.
Ruby Mariam RajuDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570 015, India.
Saleem JavidDepartment of Pharmaceutical Chemistry, Farooqia College of Pharmacy, Mysuru 570 015, India.
Madhusudan N PurohitDepartment of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru 570 015, India.
JSS Academy of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main objective of this research was to develop novel compounds from readily accessed natural products especially eugenol with potential biological activity. Eugenol, the principal chemical constituent of clove (

Indexed as

EugenolPPAR gammaAlbuminsAnti-Inflammatory AgentsHumansInflammationMolecular Docking SimulationMolecular Dynamics SimulationPPAR-gamma AgonistsSpectroscopy, Fourier Transform InfraredStructure-Activity RelationshipAlbuminsAnti-Inflammatory AgentsEugenolPPAR gammaPPAR-gamma Agonistsanti-inflammatory activityeugenol derivativesmolecular dockingpharmacophorestructure–activity relationship

Identifiers

PMID37175309
PMCPMC10180488
OpenAlexW4372337872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.