Evidence map›Paper›PMID 37175237›Full record

ArticleMolecules (Basel, Switzerland)2023

Lipid Mediators Metabolic Chaos of Asthmatic Mice Reversed by Rosmarinic Acid.

Tuo Qin, Xiaojuan Rong, Xiaohui Zhang, Lingfei Kong, Yutong Kang, Xuanlin Liu, Mengying Hu, Handong Liang, Cai Tie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Tuo QinState Key Laboratory Coal Resources and Safe Mining, China University of Mining and Technology-Beijing, Ding11 Xueyuan Road, Beijing 100083, China.
Xiaojuan RongXinjiang Institute of Material Medica, South Xinhua Road 140, Urumqi 830004, China.
Xiaohui ZhangState Key Laboratory of Natural and Biomimetic Drugs, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Lingfei KongState Key Laboratory Coal Resources and Safe Mining, China University of Mining and Technology-Beijing, Ding11 Xueyuan Road, Beijing 100083, China.
Yutong KangXinjiang Institute of Material Medica, South Xinhua Road 140, Urumqi 830004, China.
Xuanlin LiuXinjiang Institute of Material Medica, South Xinhua Road 140, Urumqi 830004, China.
Mengying HuXinjiang Institute of Material Medica, South Xinhua Road 140, Urumqi 830004, China.
Handong LiangState Key Laboratory Coal Resources and Safe Mining, China University of Mining and Technology-Beijing, Ding11 Xueyuan Road, Beijing 100083, China.
Cai TieState Key Laboratory Coal Resources and Safe Mining, China University of Mining and Technology-Beijing, Ding11 Xueyuan Road, Beijing 100083, China.
China University of Mining and Technology · CNXinjiang Technical Institute of Physics & Chemistry · CNPeking University · CN

Funding

National Natural Science Foundation of China 81960752Open Fund of the State Key Laboratory Coal Resources and Safe Mining SKLCRSM21KFA11Tianshan Youth Project 2020Q047
6 · The paper itself

Abstract

BACKGROUND AND

objectiveAsthma is a common chronic inflammatory disease of the airways with no known cure. Lipid mediators (LMs) are a kind of inflammatory signaling molecules which are believed to be involved in the development of asthma. MATERIALS AND

methodsAnti-inflammatory effect of SXCF and RosA was assessed using OVA-induced asthma model mice by UPLC-MS/MS method.

resultsOverall, RosA played a critical role in anti-asthma treatment. In total, 90% of LMs species that were significantly regulated by SXCF were covered. On the most important LMs associated with asthma, RosA equivalent induced similar effects as SXCF did. It is believed that some constituents in SXCF could neutralize RosA excessive impacts on LMs.

Indexed as

AsthmaTandem Mass SpectrometryAnimalsAnti-Inflammatory AgentsBronchoalveolar Lavage FluidChromatography, LiquidCytokinesDisease Models, AnimalHyssopus PlantLipidsMiceMice, Inbred BALB COvalbuminRosmarinic AcidAnti-Inflammatory AgentsCytokinesLipidsOvalbuminRosmarinic Acidasthmainflammationlipid mediators (LMs)rosmarinic acid (RosA)

Identifiers

PMID37175237
PMCPMC10179739
OpenAlexW4367625037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.