Evidence map›Paper›PMID 37175191›Full record

ArticleMolecules (Basel, Switzerland)2023

A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity.

Taur Prakash Pandurang, Joseph Cacaccio, Farukh A Durrani, Mykhaylo Dukh, Ajyal Z Alsaleh, Munawwar Sajjad, Francis D'Souza, Dalip Kumar, Ravindra K Pandey

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Refining antimicrobial photodynamic therapy: effect of charge distribution and central metal ion in fluorinated porphyrins on effective control of planktonic and biofilm bacterial forms.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Taur Prakash PandurangDepartment of Chemistry, Birla Institute of Technology and Science, Pilani 333031, India.
Joseph CacaccioPhotodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Farukh A DurraniPhotodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Mykhaylo DukhPhotodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Ajyal Z AlsalehDepartment of Chemistry, University of North Texas, 1155 Union Circle, Denton, TX 76203, USA.
Munawwar SajjadDepartment of Nuclear Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14221, USA.
Francis D'SouzaDepartment of Chemistry, University of North Texas, 1155 Union Circle, Denton, TX 76203, USA.ORCID 0000-0003-3815-8949
Dalip KumarDepartment of Chemistry, Birla Institute of Technology and Science, Pilani 333031, India.
Ravindra K PandeyPhotodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Roswell Park Comprehensive Cancer Center · USBirla Institute of Technology and Science, Pilani · INUniversity of North Texas · USUniversity at Buffalo, State University of New York · US

Funding

StatisticsP01CA055791 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI PANDEY, RAVINDRA K. · 1992 to 2019
$36.0M
NIH HHS CA55791 and P30CA016056
6 · The paper itself

Abstract

To investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1'-(

Indexed as

NeoplasmsPhotochemotherapyAnimalsCell Line, TumorChlorophyllChlorophyll AMaleMicePhotosensitizing AgentsChlorophyllChlorophyll APhotosensitizing Agentsphotodynamic therapyphotosensitizersstructure-activity relationship

Identifiers

PMID37175191
PMCPMC10180080
OpenAlexW4367317790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.