Evidence map›Paper›PMID 37175158›Full record

ArticleMolecules (Basel, Switzerland)2023

Modulating Substrate Specificity of

Karen Rodríguez-Núñez, Alejandra Cortés-Monroy, Marcela Serey, Yunus Ensari, Mehdi D Davari, Claudia Bernal, Ronny Martinez

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Karen Rodríguez-NúñezDepartamento de Ingeniería en Alimentos, Universidad de La Serena, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.ORCID 0000-0001-7644-4482
Alejandra Cortés-MonroyDepartamento de Ingeniería en Alimentos, Universidad de La Serena, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.
Marcela SereyDepartamento de Ingeniería en Alimentos, Universidad de La Serena, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.ORCID 0000-0002-5535-8857
Yunus EnsariDepartment of Bioengineering, Faculty of Engineering and Architecture, Kafkas University, Kars 36000, Turkey.ORCID 0000-0002-4757-4197
Mehdi D DavariDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle, Germany.ORCID 0000-0003-0089-7156
Claudia BernalInstituto de Investigación Multidisciplinaria en Ciencia y Tecnología, Universidad de La Serena, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.ORCID 0000-0001-9117-0483
Ronny MartinezDepartamento de Ingeniería en Alimentos, Universidad de La Serena, Av. Raúl Bitrán 1305, La Serena 1720010, Chile.ORCID 0000-0001-6092-1635
University of La Serena · CLKafkas University · TRLeibniz Institute of Plant Biochemistry · DE

Funding

Agencia Nacional de Investigación y Desarrollo Fondecyt 1200466
6 · The paper itself

Abstract

Histamine is a biogenic amine found in fish-derived and fermented food products with physiological relevance since its concentration is proportional to food spoilage and health risk for sensitive consumers. There are various analytical methods for histamine quantification from food samples; however, a simple and quick enzymatic detection and quantification method is highly desirable. Histamine dehydrogenase (HDH) is a candidate for enzymatic histamine detection; however, other biogenic amines can change its activity or produce false positive results with an observed substrate inhibition at higher concentrations. In this work, we studied the effect of site saturation mutagenesis in

Indexed as

AgmatineRhizobiumAnimalsBiogenic AminesFood QualityHistamineOxidoreductases Acting on CH-NH Group DonorsProtein EngineeringSubstrate SpecificityAgmatineBiogenic AminesHistaminehistamine dehydrogenaseOxidoreductases Acting on CH-NH Group Donorsagmatinedehydrogenasediaminopropaneenzyme engineeringhistamineprotein design

Identifiers

PMID37175158
PMCPMC10180351
OpenAlexW4367183517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.