ArticleMolecules (Basel, Switzerland)2023
Alginate-Chitosan Membranes for the Encapsulation of Lavender Essential Oil and Development of Biomedical Applications Related to Wound Healing.
Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Effect of Biopolymer Additives on Functional Properties of Alginate-Based Composite Hydrogels.Gels (Basel, Switzerland) · 2026Review
- Anti-Inflammatory Effect ofACS omega · 2026Article
- Preparation of Sustainable Alginate/Chitosan Blend Films by Thermo-Compression for Diverse Applications.Gels (Basel, Switzerland) · 2026Article
- Innovative Applications of Marine Macroalgae Polysaccharides in Tissue Engineering and Drug Delivery: A Review Study.Health science reports · 2025Article
- Antibacterial activity of a conventional hydrogel and a nanoparticle based hydrogel containing Satureja khuzestanica essential oil.Scientific reports · 2025Article
- Antibacterial Composites Based on Alginate/Egg White and ZnO Nanoparticles with the Addition of Essential Oils.Gels (Basel, Switzerland) · 2025Article
- Herbal bioactive-loaded biopolymeric formulations for wound healing applications.RSC advances · 2025Review
- Encapsulated essential oils in protein-polysaccharide biopolymers: characteristics and applications in the biomedical and food industries.Food science and biotechnology · 2025Review
- Biomimetic Chitosan-Based Hydrogels for Sustainable Wound Healing With AI/ML Insights.IEEE open journal of engineering in medicine and biology · 2025Article
- Hydrogels with Essential Oils: Recent Advances in Designs and Applications.Gels (Basel, Switzerland) · 2024Review
- Polymer-Based Wound Dressings Loaded with Essential Oil for the Treatment of Wounds: A Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- How the combination of alginate and chitosan can fabricate a hydrogel with favorable properties for wound healing.Heliyon · 2024Review
- Development and characterization of a topical gel, containing lavender (Lavandula angustifolia) oil loaded solid lipid nanoparticles.BMC complementary medicine and therapies · 2024Article
- Plant-Based Films and Hydrogels for Wound Healing.Microorganisms · 2024Review
- Antibacterial Activity Assessment of Chitosan/Alginate Lavender Essential Oil Membranes for Biomedical Applications.Membranes · 2024Article
- Alginate-Based Hydrogels Enriched with Lavender Essential Oil: Evaluation of Physicochemical Properties, Antimicrobial Activity, and In Vivo Biocompatibility.Pharmaceutics · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
Biopolymers such as chitosan (CHT) or alginate (ALG) are among the most prominent for health-related applications due to their broad bioactivity. Their combination for the preparation of membranes is hereby proposed as an application for wound healing with the incorporation of lavender essential oil (LEO), widely known for its antioxidant and antimicrobial properties. The preparation of CHT, CHT + LEO, ALG, ALG + LEO, and CHT/ALG + LEO membranes was accomplished, and its composition was analyzed using Fourier Transform Infrared Spectroscopy (FTIR). The water absorption capacity and oil release profile of the membranes revealed higher water uptake capacity when a lower LEO release was obtained. The combined CHT/ALG + LEO film showed a water uptake percentage of 638% after 48 h and a maximum LEO release concentration of 42 mg/L. Cytotoxicity and biocompatibility of the prepared membranes were studied using a HaCaT cell line, with an assessment of cell viability regarding film leachables, DNA quantification, and DAPI-phalloidin staining. The results revealed that the indirect contact of the prepared membranes via its leachables does not compromise cell viability, and upon direct contact, cells do not adhere or proliferate on the surface of the membranes. Moreover, the CHT/ALG + LEO membrane increases cell proliferation, making it suitable for applications in wound healing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.