Evidence map›Paper›PMID 37175090›Full record

ArticleMolecules (Basel, Switzerland)2023

Anxiolytic-like Effects and Quantitative EEG Profile of Palmitone Induces Responses Like Buspirone Rather Than Diazepam as Clinical Drugs.

Daniela Onofre-Campos, María Eva González-Trujano, Gabriel Fernando Moreno-Pérez, Fernando Narváez-González, José David González-Gómez, Benjamín Villasana-Salazar, David Martínez-Vargas

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Bioassay-Guided Fractionation ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Daniela Onofre-CamposLaboratorio de Neurofarmacología de Productos Naturales, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calz. México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico.ORCID 0009-0000-5502-8519
María Eva González-TrujanoLaboratorio de Neurofarmacología de Productos Naturales, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calz. México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico.ORCID 0000-0002-4399-1508
Gabriel Fernando Moreno-PérezLaboratorio de Neurofarmacología de Productos Naturales, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calz. México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico.ORCID 0000-0003-1968-8813
Fernando Narváez-GonzálezISSSTE Hospital Regional General Ignacio Zaragoza, Calz. Ignacio Zaragoza 1840, Juan Escutia, Iztapalapa, Ciudad de México 09100, Mexico.
José David González-GómezLaboratorio de Neurofisiología del Control y la Regulación, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calz. México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico.
Benjamín Villasana-SalazarLaboratorio de Neurofisiología del Control y la Regulación, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calz. México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico.ORCID 0000-0003-3145-8906
David Martínez-VargasLaboratorio de Neurofisiología del Control y la Regulación, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Calz. México-Xochimilco 101, Col. San Lorenzo Huipulco, Tlalpan, Ciudad de México 14370, Mexico.ORCID 0000-0002-6392-1670
Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXInstitute for Social Security and Services for State Workers · MXUniversidad Autónoma Metropolitana · MX

Funding

CONACYT 226454CONACYT 256448
6 · The paper itself

Abstract

Anxiety is a mental disorder with a growing worldwide incidence due to the SARS-CoV-2 virus pandemic. Pharmacological therapy includes drugs such as benzodiazepines (BDZs) or azapirones like buspirone (BUSP) or analogs, which unfortunately produce severe adverse effects or no immediate response, respectively. Medicinal plants or their bioactive metabolites are a shared global alternative to treat anxiety. Palmitone is one active compound isolated from

Indexed as

Anti-Anxiety AgentsCOVID-198-Hydroxy-2-(di-n-propylamino)tetralinAnimalsBuspironeDiazepamElectroencephalographyHydrocarbonsKetonesMiceReceptor, Serotonin, 5-HT1ASARS-CoV-2Serotonin Receptor Agonists8-Hydroxy-2-(di-n-propylamino)tetralinAnti-Anxiety AgentsBuspironeDiazepamHydrocarbonsKetonespalmitoneReceptor, Serotonin, 5-HT1ASerotonin Receptor Agonists16-hentriacontanoneanxietydelta bandelectroencephalographyfatty acidspalmitone

Identifiers

PMID37175090
PMCPMC10180017
OpenAlexW4366975087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.