Evidence map›Paper›PMID 37175078›Full record

ArticleMolecules (Basel, Switzerland)2023

Outlook on Chronic Venous Disease Treatment: Phytochemical Screening, In Vitro Antioxidant Activity and In Silico Studies for Three Vegetal Extracts.

Andreea Roxana Ungureanu, Carmen Lidia Chițescu, Emanuela Alice Luță, Alina Moroșan, Dan Eduard Mihaiescu, Dragoș Paul Mihai, Liliana Costea, Emma Adriana Ozon, Ancuța Cătălina Fița, Teodora Dalila Balaci and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Investigation of Anticonvulsant Potential ofInternational journal of molecular sciences · 2025
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  5. Inhibitory Effects onPlants (Basel, Switzerland) · 2024
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  7. Antioxidant and Cytotoxic Properties ofMolecules (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Superior Valorisation ofMolecules (Basel, Switzerland) · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Andreea Roxana UngureanuFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.ORCID 0009-0001-1228-9425
Carmen Lidia ChițescuFaculty of Medicine and Pharmacy, Dunărea de Jos University of Galați, A.I. Cuza 35, 800010 Galați, Romania.ORCID 0000-0002-3212-7431
Emanuela Alice LuțăFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.ORCID 0000-0002-6903-3260
Alina MoroșanFaculty of Chemical Engineering and Biotechnologies, University of Politehnica, Gheorghe Polizu 1-7, 011061 Bucharest, Romania.ORCID 0000-0003-1437-6570
Dan Eduard MihaiescuFaculty of Chemical Engineering and Biotechnologies, University of Politehnica, Gheorghe Polizu 1-7, 011061 Bucharest, Romania.
Dragoș Paul MihaiFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.ORCID 0000-0003-2880-9381
Liliana CosteaFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.
Emma Adriana OzonFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.
Ancuța Cătălina FițaFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.ORCID 0000-0002-4705-4204
Teodora Dalila BalaciFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.
Rica BoscencuFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.
Cerasela Elena GîrdFaculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Traian Vuia 6, 020956 Bucharest, Romania.ORCID 0000-0003-4372-4335
Carol Davila University of Medicine and Pharmacy · ROUniversitatea Națională de Știință și Tehnologie Politehnica București · RO"Dunarea de Jos" University of Galati · RO

Funding

Carol Davila University of Medicine and Pharmacy POCU 154722: Net4SCIENCE
6 · The paper itself

Abstract

Chronic venous disease is one of the most common vascular diseases; the signs and symptoms are varied and are often neglected in the early stages. Vascular damage is based on proinflammatory, prothrombotic, prooxidant activity and increased expression of several matrix metalloproteinases (MMPs). The aim of this research is preparation and preliminary characterization of three vegetal extracts (

Indexed as

AntioxidantsVascular DiseasesBenzothiazolesCalendulaHumansMolecular Docking SimulationPhytochemicalsPlant ExtractsSulfonic Acids2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAntioxidantsBenzothiazolesCalendula extractPhytochemicalsPlant ExtractsSulfonic Acidsantioxidant activityCalendulae flos extractchronic venous diseaseGinkgo bilobae folium extractmatrix metalloproteinasemolecular dockingphytochemical compositionSophorae flos extract

Identifiers

PMID37175078
PMCPMC10180301
OpenAlexW4366998903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.