Evidence map›Paper›PMID 37175071›Full record

ArticleMolecules (Basel, Switzerland)2023

The Antimicrobial Peptide γ-Thionin from Habanero Chile (

Luis José Flores-Alvarez, Paola Jiménez-Alcántar, Alejandra Ochoa-Zarzosa, Joel E López-Meza

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Luis José Flores-AlvarezCentro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Posta Veterinaria, Morelia C.P. 58893, Mexico.
Paola Jiménez-AlcántarCentro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Posta Veterinaria, Morelia C.P. 58893, Mexico.
Alejandra Ochoa-ZarzosaCentro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Posta Veterinaria, Morelia C.P. 58893, Mexico.ORCID 0000-0003-3441-2989
Joel E López-MezaCentro Multidisciplinario de Estudios en Biotecnología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Posta Veterinaria, Morelia C.P. 58893, Mexico.ORCID 0000-0002-3269-9202
Universidad Michoacana de San Nicolás de Hidalgo · MX

Funding

Consejo Nacional de Ciencia y Tecnología CB-2013-221363 and INFR-2014-230603Universidad Michoacana de San Nicolás de Hidalgo CIC 14.5
6 · The paper itself

Abstract

Cancer is a relevant health problem worldwide. In 2020, leukemias represented the 13th most commonly reported cancer cases worldwide but the 10th most likely to cause deaths. There has been a progressive increase in the efficacy of treatments for leukemias; however, these still generate important side effects, so it is imperative to search for new alternatives. Defensins are a group of antimicrobial peptides with activity against cancer cells. However, the cytotoxic mechanism of these peptides has been described mainly for animal defensins. This study shows that defensin γ-thionin (

Indexed as

Antineoplastic AgentsCapsicumLeukemia, Myelogenous, Chronic, BCR-ABL PositiveThioninsAnimalsAntimicrobial PeptidesApoptosisCaspasesChileDefensinsEpigenesis, GeneticHumansK562 CellsLeukocytes, MononuclearLysinePeptidesAntimicrobial PeptidesAntineoplastic AgentsCaspasesDefensinsLysinePeptidesThioninsantimicrobial peptidesapoptosiscalpainsepigenetic regulationleukemiaγ-thionin

Identifiers

PMID37175071
PMCPMC10180109
OpenAlexW4366975395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.