Evidence map›Paper›PMID 37175051›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Microembolizations in the Arterial Cerebral Circulation in Patients with Atrial Fibrillation Ablation Using the Cryoballoon Technique-Protocol and Methodology of a Prospective Observational Study.

Damir Erkapic, Marko Aleksic, Konstantinos Roussopoulos, Kay Felix Weipert, Korkut Sözener, Karel Kostev, Jens Allendörfer, Josef Rosenbauer, Dursun Guenduez, Christian Tanislav

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Microembolizations in the arterial cerebral circulation during atrial fibrillation ablation: cryoballoon technique advantages and neurocognitive safety-results of a prospective observational study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Damir ErkapicDepartment of Cardiology, Rhythmology and Angiology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.
Marko AleksicDepartment of Cardiology, Rhythmology and Angiology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.
Konstantinos RoussopoulosDepartment of Cardiology, Rhythmology and Angiology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.
Kay Felix WeipertDepartment of Cardiology, Rhythmology and Angiology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.
Korkut SözenerDepartment of Cardiology, Rhythmology and Angiology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.
Karel KostevEpidemiology, IQVIA, Unterschweinstiege 2-14, 60549 Frankfurt am Main, Germany.ORCID 0000-0002-2124-7227
Jens AllendörferNeurological Clinic Bad Salzhausen, 63667 Nidda, Germany.
Josef RosenbauerDepartment of Cardiology, Rhythmology and Angiology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.
Dursun GuenduezDepartment of Cardiology, Rhythmology and Angiology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.
Christian TanislavDepartment of Geriatrics and Neurology, Diakonie Klinikum Jung Stilling, 57074 Siegen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is considerable uncertainty regarding the impact of microembolic signals (MESs) on neuropsychological abilities in patients receiving pulmonary vein isolation and beyond using the cryoballoon technique. We conducted the largest prospective observational study on this topic, providing insights into the gradual unmasking of procedure-related MESs and their impacts on neuropsychological outcomes. MESs were continuously detected periprocedurally using transcranial Doppler ultrasonography. Neuropsychological status was evaluated comprehensively using the CERAD Plus test battery, which consists of 11 neuropsychological subtests. Patients with atrial fibrillation were included in the study with an equal distribution (50:50) of paroxysmal or persistent presentations. Of 167 consecutive eligible patients, 100 were included within the study enrollment period from February 2021 to August 2022. The study, including the documentation of all follow-up visits, ended in November 2022. This paper focuses on describing the study protocol and methodology and presenting the baseline data.

Indexed as

ablationatrial fibrillationcryoballoonmicroembolizationneuropsychological outcome

Identifiers

PMID37175051
PMCPMC10178285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.