SAA-UNet: Spatial Attention and Attention Gate UNet for COVID-19 Pneumonia Segmentation from Computed Tomography.

The disaster of the COVID-19 pandemic has claimed numerous lives and wreaked havoc on the entire world due to its transmissible nature. One of the complications of COVID-19 is pneumonia. Different radiography methods, particularly computed tomography (CT), have shown outstanding performance in effectively diagnosing pneumonia. In this paper, we propose a spatial attention and attention gate UNet model (SAA-UNet) inspired by spatial attention UNet (SA-UNet) and attention UNet (Att-UNet) to deal with the problem of infection segmentation in the lungs. The proposed method was applied to the MedSeg, Radiopaedia 9P, combination of MedSeg and Radiopaedia 9P, and Zenodo 20P datasets. The proposed method showed good infection segmentation results (two classes: infection and background) with an average Dice similarity coefficient of 0.85, 0.94, 0.91, and 0.93 and a mean intersection over union (IOU) of 0.78, 0.90, 0.86, and 0.87, respectively, on the four datasets mentioned above. Moreover, it also performed well in multi-class segmentation with average Dice similarity coefficients of 0.693, 0.89, 0.87, and 0.93 and IOU scores of 0.68, 0.87, 0.78, and 0.89 on the four datasets, respectively. Classification accuracies of more than 97% were achieved for all four datasets. The F1-scores for the MedSeg, Radiopaedia P9, combination of MedSeg and Radiopaedia P9, and Zenodo 20P datasets were 0.865, 0.943, 0.917, and 0.926, respectively, for the binary classification. For multi-class classification, accuracies of more than 96% were achieved on all four datasets. The experimental results showed that the framework proposed can effectively and efficiently segment COVID-19 infection on CT images with different contrast and utilize this to aid in diagnosing and treating pneumonia caused by COVID-19.