Evidence map›Paper›PMID 37174994›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Alterations in Macular Microvasculature in Pterygium Patients Measured by OCT Angiography.

Yingjun Cai, Zhenkai Wu, Ruolan Yuan, Pingbao Wang, Huizhuo Xu, Yi Xu, Xueyan Yao, Hua Wang, Jing Zou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yingjun CaiEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.
Zhenkai WuThe First People's Hospital of Changde, Changde 415000, China.
Ruolan YuanEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.
Pingbao WangEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.
Huizhuo XuEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.
Yi XuEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.
Xueyan YaoEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.
Hua WangEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.
Jing ZouEye Center of Xiangya Hospital, Hunan Key Laboratory of Ophthalmology, Central South University, Changsha 410008, China.ORCID 0000-0002-0976-7078
Central South University · CNThe First People's Hospital of Changde · CN

Funding

National Natural Science Foundation of China 81170823
6 · The paper itself

Abstract

Previous studies have reported an association between pterygia and maculopathy, yet the underlying mechanisms and alterations to the macular microvasculature in pterygium patients have yet to be fully elucidated. Our study conducted an analysis of macular superficial vessel length density (VLD) and vessel perfusion density (VPD) to establish associations between the conjunctival and macular microvasculature in patients with unilateral and bilateral pterygia. We revealed a loss of macular microvasculature in the outer nasal (ON) region in both unilateral and bilateral pterygium patients. VLD was significantly decreased in both pterygium groups in the ON region, and VPD was notably lower in bilateral pterygium patients in the same area. Furthermore, in unilateral pterygium patients, the vessel percent pixel coverage (PPC) of the pterygium and the area of the pterygium exhibited a negative correlation with VLD in the ON region. Multiple stepwise linear regression models indicated that the PPC could best predict VLP in the ON region. Taken together, our findings suggest that patients with pterygia may be more susceptible to macular diseases, and this may be due to a compensatory increase in blood perfusion via the anterior ciliary artery. These results underscore the importance of managing maculopathy in patients with pterygia.

Indexed as

conjunctival microvascularmacular microvascularoptical coherence tomography angiographypterygium

Identifiers

PMID37174994
PMCPMC10177751
OpenAlexW4367626996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.