Evidence map›Paper›PMID 37174988›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Effectiveness of Stereotactic Ablative Radiotherapy for Systemic Therapy Respondents with Inoperable Pulmonary Oligometastases and Oligoprogression.

Chin-Beng Ho, Jo-Ting Tsai, Chun-You Chen, Her-Shyong Shiah, Hsuan-Yu Chen, Lai-Lei Ting, Chia-Chun Kuo, I-Chun Lai, Hsin-Yi Lai, Chi-Li Chung and 6 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Chin-Beng HoPh.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0001-9370-4012
Jo-Ting TsaiDepartment of Radiation Oncology, Taipei Medical University-Shuang Ho Hospital, New Taipei City 235041, Taiwan.
Chun-You ChenTaipei Cancer Center, Taipei Medical University, Taipei 110301, Taiwan.
Her-Shyong ShiahDivision of Hematology and Oncology, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231016, Taiwan.
Hsuan-Yu ChenPh.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0003-0358-9132
Lai-Lei TingDepartment of Radiation Oncology, Taipei Medical University Hospital, Taipei 110301, Taiwan.
Chia-Chun KuoPh.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0002-4487-0265
I-Chun LaiDepartment of Heavy Particles and Radiation Oncology, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
Hsin-Yi LaiDepartment of Medical Imaging, Taipei Medical University Hospital, Taipei Medical University, Taipei 110301, Taiwan.
Chi-Li ChungDivision of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0003-0656-976X
Kai-Ling LeeDivision of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei 110301, Taiwan.
Huey-En TzengGraduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 110301, Taiwan.
Kuen-Haur LeePh.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0002-6354-3315
Hsin-Lun LeeDepartment of Radiation Oncology, Taipei Medical University Hospital, Taipei 110301, Taiwan.
Shang-Wen ChenDepartment of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Jeng-Fong ChiouPh.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei Medical University, Taipei 110301, Taiwan.
Taipei Medical University Hospital · TWChina Medical University · TWNational Yang Ming Chiao Tung University · TWTaichung Veterans General Hospital · TWTaipei Medical University-Shuang Ho Hospital · TWTaipei Tzu Chi Hospital · TWTaipei Veterans General Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotactic ablative radiotherapy (SABR) may improve survival in patients with inoperable pulmonary oligometastases. However, the impact of pulmonary oligometastatic status after systemic therapy on SABR outcomes remains unclear. Hence, we investigated the outcomes of SABR in 45 patients with 77 lung tumors and the prognostic value of pulmonary oligoprogression. Eligibility criteria were pulmonary oligometastases (defined as ≤5 metastatic lung tumors), controlled extrapulmonary disease (EPD) after front-line systemic therapy, SABR as primary local treatment for inoperable pulmonary metastases, and consecutive imaging follow-up. Oligometastatic lung tumor was classified into controlled or oligoprogressive status. Overall survival (OS), in-field progression-free survival (IFPFS), out-field progression-free survival (OFPFS), and prognostic variables were evaluated. With 21.8 months median follow-up, the median OS, IFPFS, and OFPFS were 28.3, not reached, and 6.5 months, respectively. Two-year OS, IFPFS, and OFPFS rates were 56.0%, 74.2%, and 17.3%, respectively. Oligoprogressive status (

Indexed as

extrapulmonary diseasemetastasectomyoligometastasesoligoprogressionpulmonary metastasesstereotactic ablative radiotherapy (SABR)

Identifiers

PMID37174988
PMCPMC10177978
OpenAlexW4367624508

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.