Evidence map›Paper›PMID 37174964›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Detection of SARS-CoV-2 Variants via Different Diagnostics Assays Based on Single-Nucleotide Polymorphism Analysis.

Eliana Specchiarello, Giulia Matusali, Fabrizio Carletti, Cesare Ernesto Maria Gruber, Lavinia Fabeni, Claudia Minosse, Emanuela Giombini, Martina Rueca, Fabrizio Maggi, Alessandra Amendola and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Mutational Landscape of SARS-CoV-2.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Eliana SpecchiarelloLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0001-5277-3417
Giulia MatusaliLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0002-2948-4243
Fabrizio CarlettiLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0003-1952-5117
Cesare Ernesto Maria GruberLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0002-8831-3380
Lavinia FabeniLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.
Claudia MinosseLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0001-7833-9539
Emanuela GiombiniLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0003-2237-9755
Martina RuecaLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0001-5162-046X
Fabrizio MaggiLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.
Alessandra AmendolaLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0002-7063-0222
Anna Rosa GarbugliaLaboratory of Virology, National Institute for Infectious Diseases (INMI) Lazzaro Spallanzani (IRCCS), 00149 Rome, Italy.ORCID 0000-0002-2687-8642
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · IT

Funding

Ministero della Salute ricerca corrente linea 1
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by fast evolution with the appearance of several variants. Next-Generation Sequencing (NGS) technology is considered the gold standard for monitoring known and new SARS-CoV-2 variants. However, the complexity of this technology renders this approach impracticable in laboratories located in areas with limited resources. We analyzed the capability of the ThermoFisher TaqPath COVID-19 RT-PCR (TaqPath) and the Seegene Novaplex SARS-CoV-2 Variant assay (Novaplex) to detect Omicron variants; the Allplex VariantII (Allplex) was also evaluated for Delta variants. Sanger sequencing (SaS) was the reference method. The results obtained with

Indexed as

molecular diagnosisSARS-CoV-2SARS-CoV-2 variant assaySARS-CoV-2 variantssingle-nucleotide polymorphism (SNP)

Identifiers

PMID37174964
PMCPMC10177602
OpenAlexW4367317402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.