Evidence map›Paper›PMID 37174922›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Evolution of the Probe-Based Loop-Mediated Isothermal Amplification (LAMP) Assays in Pathogen Detection.

Xiaoling Zhang, Yongjuan Zhao, Yi Zeng, Chiyu Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Point of Care Testing and Recombinase Polymerase Amplification.Journal of clinical laboratory analysis · 2026
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  4. Review
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  12. Biology methods & protocols · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaoling ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Yongjuan ZhaoShanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Yi ZengShanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Chiyu ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
Shanghai Public Health Clinical Center · CN

Funding

Shanghai Public Health Clinical Center hospital-level scientific research project KY -GW-2023-32Shanghai Science& Technology Innovation Action Program 21Y11900500
6 · The paper itself

Abstract

Loop-mediated isothermal amplification (LAMP), as the rank one alternative to a polymerase chain reaction (PCR), has been widely applied in point-of-care testing (POCT) due to its rapid, simple, and cost-effective characteristics. However, it is difficult to achieve real-time monitoring and multiplex detection with the traditional LAMP method. In addition, these approaches that use turbidimetry, sequence-independent intercalating dyes, or pH-sensitive indicators to indirectly reflect amplification can result in false-positive results if non-specific amplification occurs. To fulfill the needs of specific target detection and one-pot multiplex detection, a variety of probe-based LAMP assays have been developed. This review focuses on the principles of these assays, summarizes their applications in pathogen detection, and discusses their features and advantages over the traditional LAMP methods.

Indexed as

LAMPpathogen detectionprobesensitivityspecificity

Identifiers

PMID37174922
PMCPMC10177487
OpenAlexW4366826031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.