Evidence map›Paper›PMID 37174744›Full record

ReviewCells2023

The Role of Polo-Like Kinase 1 in Regulating the Forkhead Box Family Transcription Factors.

Xavier T R Moore, Lilia Gheghiani, Zheng Fu

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xavier T R MooreDepartment of Biology, Virginia Commonwealth University, Richmond, VA 23284, USA.ORCID 0000-0003-0363-8846
Lilia GheghianiDepartment of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0002-0713-1789
Zheng FuDepartment of Human and Molecular Genetics, VCU Institute of Molecular Medicine, Massey Cancer Center, Virginia Commonwealth University, School of Medicine, Richmond, VA 23298, USA.ORCID 0000-0003-0837-3728
Virginia Commonwealth University · US

Funding

The role of PLK1 in prostate cancerR01CA191002 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI FU, ZHENG · 2016 to 2020
$1.7M
NIH HHS R01 CA191002
6 · The paper itself

Abstract

Polo-like kinase 1 (PLK1) is a serine/threonine kinase with more than 600 phosphorylation substrates through which it regulates many biological processes, including mitosis, apoptosis, metabolism, RNA processing, vesicle transport, and G

Indexed as

Forkhead Transcription FactorsNeoplasmsCell Cycle ProteinsHumansPolo-Like Kinase 1Protein Serine-Threonine KinasesCell Cycle ProteinsForkhead Transcription FactorsFOXK1 protein, humanPolo-Like Kinase 1Protein Serine-Threonine KinasesFOX familyoncogenetargeted therapytranscription factortumor suppressor

Identifiers

PMID37174744
PMCPMC10177174
OpenAlexW4376630961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.