Evidence map›Paper›PMID 37174702›Full record

ArticleCells2023

Analysis of Immunophenotypic Changes during Ex Vivo Human Erythropoiesis and Its Application in the Study of Normal and Defective Erythropoiesis.

Shobhita Katiyar, Arunim Shah, Khaliqur Rahman, Naresh Kumar Tripathy, Rajesh Kashyap, Soniya Nityanand, Chandra Prakash Chaturvedi

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shobhita KatiyarStem Cell Research Center, Department of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.ORCID 0000-0001-9193-4068
Arunim ShahStem Cell Research Center, Department of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.ORCID 0000-0002-7107-7457
Khaliqur RahmanDepartment of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Naresh Kumar TripathyDepartment of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.ORCID 0000-0002-2621-802X
Rajesh KashyapDepartment of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.ORCID 0000-0002-6645-8052
Soniya NityanandDepartment of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.
Chandra Prakash ChaturvediStem Cell Research Center, Department of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India.ORCID 0000-0002-4017-430X
Sanjay Gandhi Post Graduate Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erythropoiesis is a highly regulated process and undergoes several genotypic and phenotypic changes during differentiation. The phenotypic changes can be evaluated using a combination of cell surface markers expressed at different cellular stages of erythropoiesis using FACS. However, limited studies are available on the in-depth phenotypic characterization of progenitors from human adult hematopoietic stem and progenitor cells (HSPCs) to red blood cells. Therefore, using a set of designed marker panels, in the current study we have kinetically characterized the hematopoietic, erythroid progenitors, and terminally differentiated erythroblasts ex vivo. Furthermore, the progenitor stages were explored for expression of CD117, CD31, CD41a, CD133, and CD45, along with known key markers CD36, CD71, CD105, and GPA. Additionally, we used these marker panels to study the stage-specific phenotypic changes regulated by the epigenetic regulator;

Indexed as

Erythroid Precursor CellsErythropoiesisAdultCell DifferentiationErythroblastsHumansImmunophenotypingerythropoiesisflowcytometrymarker panels

Identifiers

PMID37174702
PMCPMC10177526
OpenAlexW4368405408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.