Evidence map›Paper›PMID 37174695›Full record

ArticleCells2023

A Non-Canonical Role for the Glycosyltransferase Enzyme UGT2B17 as a Novel Constituent of the B Cell Receptor Signalosome.

Antoine Wagner, Michèle Rouleau, Lyne Villeneuve, Trang Le, Cheryl Peltier, Éric P Allain, Caroline Beaudoin, Sophie Tremblay, Fréderic Courtier, Flora Nguyen Van Long and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Antoine WagnerCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.ORCID 0000-0001-8751-4626
Michèle RouleauCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.ORCID 0000-0002-2357-1848
Lyne VilleneuveCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.
Trang LeDepartment of Medicine I, Division of Haematology and Haemostaseology, Medical University of Vienna, 1090 Vienna, Austria.
Cheryl PeltierDepartment of Internal Medicine & Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
Éric P AllainMolecular Genetics Laboratory, Dr. Georges-L-Dumont University Hospital Center, Moncton, NB E1C 2Z3, Canada.
Caroline BeaudoinCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.ORCID 0000-0003-3501-0711
Sophie TremblayCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.
Fréderic CourtierCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.
Flora Nguyen Van LongCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.
Isabelle LaverdièreCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.ORCID 0000-0003-3972-6602
Éric LévesqueCRCHUQc-UL, Faculty of Medicine, and CRC-UL, Université Laval, Québec, QC G1V 4G2, Canada.
Versha BanerjiDepartment of Internal Medicine & Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.ORCID 0000-0002-7415-8818
Katrina VanuraDepartment of Medicine I, Division of Haematology and Haemostaseology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-2217-4998
Chantal GuillemetteCentre Hospitalier Universitaire de Québec Research Center-Université Laval (CRCHUQc-UL), Faculty of Pharmacy, and Centre de Recherche sur le Cancer de l'Université Laval (CRC-UL), Université Laval, Québec, QC G1V 4G2, Canada.ORCID 0000-0002-1113-1212
Centre hospitalier universitaire de Québec · CACancerCare Manitoba · CAMedical University of Vienna · ATDr. Georges-L.-Dumont University Hospital Centre · CAUniversité Laval · CA

Funding

CIHR FRN-167269
6 · The paper itself

Abstract

In chronic lymphocytic leukemia (CLL), an elevated glycosyltransferase UGT2B17 expression (UGT2B17

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellGlucuronosyltransferaseHumansMinor Histocompatibility AntigensPhosphorylationProtein-Tyrosine KinasesReceptors, Antigen, B-CellSignal TransductionGlucuronosyltransferaseMinor Histocompatibility AntigensProtein-Tyrosine KinasesReceptors, Antigen, B-CellUGT2B17 protein, humanB cell receptorBTKcerdulatinibCLLglycosyltransferaseibrutinibUGT2B17ZAP70

Identifiers

PMID37174695
PMCPMC10177405
OpenAlexW4368377563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.