Evidence map›Paper›PMID 37174187›Full record

ArticleInternational journal of environmental research and public health2023

Barriers and Facilitators to Pre-Exposure Prophylaxis by Men Who Have Sex with Men and Community Stakeholders in Malaysia.

Aviana O Rosen, Jeffrey A Wickersham, Frederick L Altice, Antoine Khati, Iskandar Azwa, Vincent Tee, Alma Jeri-Wahrhaftig, Jeffrey Ralph Luces, Zhao Ni, Adeeba Kamarulzaman and 2 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aviana O RosenDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0002-3533-5682
Jeffrey A WickershamDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0001-7701-9162
Frederick L AlticeDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT 06510, USA.
Antoine KhatiDepartment of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT 06510, USA.
Iskandar AzwaCentre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Vincent TeeCentre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0002-6562-2666
Alma Jeri-WahrhaftigDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0003-0181-6717
Jeffrey Ralph LucesMaster of Health Research Ethics (MOHRE), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Zhao NiYale School of Nursing, Yale University, Orange, CT 06477, USA.ORCID 0000-0002-9185-9894
Adeeba KamarulzamanCentre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Rumana SaifiCentre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Roman ShresthaDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0003-4340-3101

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Development and Testing of a Mobile Application to Enhance HIV Prevention Cascade in Malaysian MSMR33TW011665 · FIC · UNIVERSITY OF CONNECTICUT STORRS · PI SHRESTHA, ROMAN · 2022 to 2024
$885k
Training in MHealth Prevention with MSMK01DA051346 · NIDA · YALE UNIVERSITY · PI SHRESTHA, ROMAN · 2020 to 2024
$862k
Integrated online-to-offline (O2O) model of care for HIV prevention and treatment among men who have sex with menR34MH130233 · NIMH · UNIVERSITY OF CONNECTICUT STORRS · PI SHRESTHA, ROMAN, WICKERSHAM, JEFFREY ALLEN · 2022 to 2024
$817k
Development and Testing of a Mobile Application to Enhance HIV Prevention Cascade in Malaysian MSMR21TW011665 · FIC · YALE UNIVERSITY · PI SHRESTHA, ROMAN · 2020 to 2021
$408k
FIC NIH HHS R21 TW011665FIC NIH HHS R33 TW011665NCATS NIH HHS UL1 TR001863NIDA NIH HHS K01 DA051346NIDA NIH HHS K01DA051346NIMH NIH HHS R34 MH130233
6 · The paper itself

Abstract

backgroundMen who have sex with men (MSM) in Malaysia are disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) is an evidence-based HIV prevention strategy; yet, uptake remains low among Malaysian MSM, who have a limited understanding of barriers to PrEP.

methodsWe employed the nominal group technique (NGT), a structured mixed-methods strategy to understand the barriers and facilitators to PrEP use among Malaysian MSM, combined with a qualitative focus group. Six virtual focus group sessions, three among MSM (

resultsSimilar barriers were reported by MSM and community stakeholders, with aggregated costs associated with PrEP care (e.g., consultation with a clinician, medication, laboratory testing) being the greatest barrier, followed by limited knowledge and awareness of PrEP. Additionally, the lack of access to PrEP providers, the complex clinical protocol for PrEP initiation and follow-up, and social stigma undermined PrEP delivery. Qualitative discussions identified potential new strategies to overcome these barriers, including expanded outreach efforts to reach hard-to-reach MSM, a 'one-stop' delivery model for PrEP services, a patient-centered decision aid to guide PrEP uptake, and easy access to LGBT-friendly PrEP providers.

conclusionCurrent barriers may be overcome through governmental subsidy for PrEP and evidence-informed shared decision aids to support both MSM and PrEP providers.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesHomosexuality, MaleHumansMalaysiaMaleAnti-HIV AgentsHIVMalaysiamen who have sex with mennominal group techniquepatient preferencespre-exposure prophylaxis

Identifiers

PMID37174187
PMCPMC10177799

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.