Evidence map›Paper›PMID 37174044›Full record

ArticleCancers2023

The Impact of Acute Systemic Inflammation Secondary to Oesophagectomy and Anastomotic Leak on Computed Tomography Body Composition Analyses.

Leo R Brown, Michael I Ramage, Ross D Dolan, Judith Sayers, Nikki Bruce, Lachlan Dick, Sharukh Sami, Donald C McMillan, Barry J A Laird, Stephen J Wigmore and 1 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Leo R BrownClinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.ORCID 0000-0001-6181-7020
Michael I RamageClinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.
Ross D DolanAcademic Unit of Surgery, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UK.ORCID 0000-0002-5272-5906
Judith SayersClinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.
Nikki BruceDepartment of General Surgery, Borders General Hospital, Melrose TD6 9BS, UK.
Lachlan DickDepartment of General Surgery, Victoria Hospital, Kirkcaldy KY2 5AH, UK.ORCID 0000-0002-4341-9501
Sharukh SamiDepartment of General Surgery, Dumfries and Galloway Royal Infirmary, Dumfries DG2 8RX, UK.
Donald C McMillanAcademic Unit of Surgery, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UK.
Barry J A LairdSt Columba's Hospice, Edinburgh EH5 3RW, UK.
Stephen J WigmoreClinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.ORCID 0000-0002-3614-8002
Richard J E SkipworthClinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.ORCID 0000-0003-1428-4078

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to longitudinally assess CT body composition analyses in patients who experienced anastomotic leak post-oesophagectomy. Consecutive patients, between 1 January 2012 and 1 January 2022 were identified from a prospectively maintained database. Changes in computed tomography (CT) body composition at the third lumbar vertebral level (remote from the site of complication) were assessed across four time points where available: staging, pre-operative/post-neoadjuvant treatment, post-leak, and late follow-up. A total of 20 patients (median 65 years, 90% male) were included, with a total of 66 computed tomography (CT) scans analysed. Of these, 16 underwent neoadjuvant chemo(radio)therapy prior to oesophagectomy. Skeletal muscle index (SMI) was significantly reduced following neoadjuvant treatment (

Indexed as

anastomotic leakbody compositioncancercomputed tomographyoesophagectomysystemic inflammation

Identifiers

PMID37174044
PMCPMC10177546

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.