Evidence map›Paper›PMID 37174016›Full record

ArticleCancers2023

Patient Breathing Motion and Delivery Specifics Influencing the Robustness of a Proton Pancreas Irradiation.

Barbara Knäusl, Franciska Lebbink, Piero Fossati, Erik Engwall, Dietmar Georg, Markus Stock

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The role of 4D particle therapy in daily patient care and research.Physics and imaging in radiation oncology · 2024
    Article
  5. Review
  6. Article
  7. Parameter based 4D dose calculations for proton therapy.Physics and imaging in radiation oncology · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barbara KnäuslDepartment of Radiation Oncology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-4031-1711
Franciska LebbinkDepartment of Radiation Oncology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-6555-9487
Piero FossatiMedAustron Ion Therapy Centre, Medical Physics, 2700 Wiener Neustadt, Austria.ORCID 0000-0001-9803-242X
Erik EngwallRaySearch Laboratories, 10430 Stockholm, Sweden.ORCID 0000-0001-8161-4829
Dietmar GeorgDepartment of Radiation Oncology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-8327-3877
Markus StockMedAustron Ion Therapy Centre, Medical Physics, 2700 Wiener Neustadt, Austria.ORCID 0000-0001-7510-7759

Funding

Gesellschaft für Forschungsförderung, Niederösterreich SC19-013
6 · The paper itself

Abstract

Motion compensation strategies in particle therapy depend on the anatomy, motion amplitude and underlying beam delivery technology. This retrospective study on pancreas patients with small moving tumours analysed existing treatment concepts and serves as a basis for future treatment strategies for patients with larger motion amplitudes as well as the transition towards carbon ion treatments. The dose distributions of 17 hypofractionated proton treatment plans were analysed using 4D dose tracking (4DDT). The recalculation of clinical treatment plans employing robust optimisation for mitigating different organ fillings was performed on phased-based 4D computed tomography (4DCT) data considering the accelerator (pulsed scanned pencil beams delivered by a synchrotron) and the breathing-time structure. The analysis confirmed the robustness of the included treatment plans concerning the interplay of beam and organ motion. The median deterioration of

Indexed as

4Ddose calculationsinterplaypancreatic cancerproton therapy

Identifiers

PMID37174016
PMCPMC10177445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.