Evidence map›Paper›PMID 37173958›Full record

ReviewCancers2023

Value of Artificial Intelligence in Evaluating Lymph Node Metastases.

Nicolò Caldonazzi, Paola Chiara Rizzo, Albino Eccher, Ilaria Girolami, Giuseppe Nicolò Fanelli, Antonio Giuseppe Naccarato, Giuseppina Bonizzi, Nicola Fusco, Giulia d'Amati, Aldo Scarpa and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  14. Digital pathology structure and deployment in Veneto: a proof-of-concept study.Virchows Archiv : an international journal of pathology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Nicolò CaldonazziDepartment of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy.
Paola Chiara RizzoDepartment of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy.
Albino EccherDepartment of Pathology and Diagnostics, University and Hospital Trust of Verona, 37126 Verona, Italy.ORCID 0000-0002-9992-5550
Ilaria GirolamiDepartment of Pathology, Lehrkrankenhaus der Paracelsus Medizinischen Privatuniversität, Provincial Hospital of Bolzano (SABES-ASDAA), 39100 Bolzano-Bozen, Italy.ORCID 0000-0003-3537-4929
Giuseppe Nicolò FanelliDivision of Pathology, Department of Translational Research, New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-7069-7980
Antonio Giuseppe NaccaratoDivision of Pathology, Department of Translational Research, New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-8195-9445
Giuseppina BonizziDivision of Pathology, IEO, Europefan Institute of Oncology IRCCS, University of Milan, 20122 Milan, Italy.
Nicola FuscoDivision of Pathology, IEO, Europefan Institute of Oncology IRCCS, University of Milan, 20122 Milan, Italy.ORCID 0000-0002-9101-9131
Giulia d'AmatiDepartment of Radiology, Oncology and Pathology, Sapienza, University of Rome, 00185 Rome, Italy.ORCID 0000-0002-6959-691X
Aldo ScarpaDepartment of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-1678-739X
Liron PantanowitzDepartment of Pathology, University of Michigan, Ann Arbor, MI 48104, USA.
Stefano MarlettaDepartment of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-7881-8767
University of Verona · ITUniversity of Milan · ITUniversity of Pisa · ITOspedale di Bolzano · ITSapienza University of Rome · ITUniversity of Michigan · US

Funding

European Union - NextGenerationEU through the Italian Ministry of University and Research under PNRR - M4C2-I1.3 Project PE_00000019 "HEAL ITALIA" B33C22001030006
6 · The paper itself

Abstract

One of the most relevant prognostic factors in cancer staging is the presence of lymph node (LN) metastasis. Evaluating lymph nodes for the presence of metastatic cancerous cells can be a lengthy, monotonous, and error-prone process. Owing to digital pathology, artificial intelligence (AI) applied to whole slide images (WSIs) of lymph nodes can be exploited for the automatic detection of metastatic tissue. The aim of this study was to review the literature regarding the implementation of AI as a tool for the detection of metastases in LNs in WSIs. A systematic literature search was conducted in PubMed and Embase databases. Studies involving the application of AI techniques to automatically analyze LN status were included. Of 4584 retrieved articles, 23 were included. Relevant articles were labeled into three categories based upon the accuracy of AI in evaluating LNs. Published data overall indicate that the application of AI in detecting LN metastases is promising and can be proficiently employed in daily pathology practice.

Indexed as

artificial intelligencedigital pathologylymph nodesmetastases

Identifiers

PMID37173958
PMCPMC10177013
OpenAlexW4367183575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.