Evidence map›Paper›PMID 37173943›Full record

ReviewCancers2023

The Role of Immunotherapy or Immuno-Chemotherapy in Non-Small Cell Lung Cancer: A Comprehensive Review.

Shehab Mohamed, Luca Bertolaccini, Domenico Galetta, Francesco Petrella, Monica Casiraghi, Filippo de Marinis, Lorenzo Spaggiari

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Cemiplimab combined with chemotherapyTherapeutic advances in medical oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shehab MohamedDepartment of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-3157-3720
Luca BertolacciniDepartment of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-1153-3334
Domenico GalettaDepartment of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-4040-7211
Francesco PetrellaDepartment of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-5945-1576
Monica CasiraghiDepartment of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-5986-7811
Filippo de MarinisDepartment of Thoracic Oncology, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Lorenzo SpaggiariDepartment of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy.
University of Milan · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITEuropean Institute of Oncology · IT

Funding

Ministero della Salute 5 x 1000Ministero della Salute Ricerca Corrente
6 · The paper itself

Abstract

Many new treatment modalities for non-small-cell carcinoma (NSCLC) have been described in the last two decades. Surgical resections remain the gold standard for early stages and may be considered for locally advanced tumors. Medical treatment has changed drastically in recent years, especially for advanced stages, for which the development of immunotherapy and molecular targeted therapy significantly increased survival and quality of life. The addition of radical surgical resection following immunotherapy or immuno-chemotherapy is feasible and safe with low surgical-related mortality and morbidity in selected patients with initially unresectable NSCLC. However, data from multiple ongoing trials with overall survival as the primary endpoint should be awaited before this strategy is introduced into the standard of care.

Indexed as

immunotherapylung cancerreviewthoracic surgery

Identifiers

PMID37173943
PMCPMC10177497
OpenAlexW4367189175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.