Trial reportPsycho-oncology2023
Meaning-centered pain coping skills training for patients with metastatic cancer: Results of a randomized controlled pilot trial.
Trial report in Psycho-oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04431830 (Meaning-Centered Pain Coping Skills Training), which is not on this map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Meaning-Centered Pain Coping Skills Training: A Randomized Pilot Trial for Patients With Advanced Cancer and Pain
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Efficacy of psychological interventions versus standard care for cancer pain: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Mind over Malignancy: A Systematic Review and Meta-Analysis of Psychological Distress, Coping, and Therapeutic Interventions in Oncology.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Effectiveness of meaning-centered interventions on anxiety and depressive symptoms, sense of meaning, and quality of life in patients with advanced cancer: a meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Effect of applying digital health in palliative care for patients with advanced cancer: a meta-analysis and systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Quality of patient-reported outcome reporting and related trial characteristics in randomized controlled trials of cancer pain: A systematic review based on the CONSORT-PRO extension.Asia-Pacific journal of oncology nursing · 2026Review
- Review
- Pilot Study of a Cognitive Behavioral Therapy Protocol via Videoconference for the Management of Pain, Emotional Distress, and Quality of Life in Mexican Patients with Cancer and Chronic Pain.Journal of clinical psychology in medical settings · 2026Article
- Initial testing of a mobile app behavioral pain coping intervention for patients with cancer: Results of a pilot randomized controlled trial.Journal of psychosocial oncology · 2026Article
- The association between health-related quality of life and the meaning of life in community-dwelling older adults.BMC geriatrics · 2026Article
- Pilot Testing of a Multicomponent Cancer Pain-Cognitive Behavioral Therapy mHealth App for Patients With Advanced Cancer.JCO clinical cancer informatics · 2025Article
- Trends in Outpatient Opioid Prescriptions for Cancer Pain Between 2016 and 2021.JCO oncology practice · 2025Article
- Belief in living a meaningful life and adjustment to chronic pain.Pain medicine (Malden, Mass.) · 2025Article
- Similarities and important distinctions between drug and behavioral intervention development.Discover psychology · 2025Review
- Article
- Article
- The role of spirituality in pain experiences among adults with cancer: an explanatory sequential mixed methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Meaning-centered pain coping skills training for patients with metastatic cancer: Protocol for a randomized controlled efficacy trial.Contemporary clinical trials · 2023Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveFor patients with advanced cancer, pain is a common and debilitating symptom that can negatively impact physical, emotional, and spiritual well-being. This trial examined the feasibility and initial effects of Meaning-Centered Pain Coping Skills Training (MCPC), a cognitive-behavioral pain management intervention with an emphasis on enhancing meaning (i.e., a personal sense of purpose, worth, and significance) and peace.
methodsWe enrolled 60 adults with stage IV solid tumor cancers and moderate-severe pain between February 2021 and February 2022. Participants were randomized 1:1 to MCPC + usual care or usual care alone. Meaning-Centered Pain Coping Skills Training consisted of four weekly 60-min individual sessions via videoconference or telephone, delivered by a trained therapist using a manualized protocol. Participants completed validated measures of pain severity, pain interference, pain self-efficacy, spiritual well-being (i.e., meaning, peace, and faith), and psychological distress at baseline and 5-week and 10-week follow-ups.
resultsAll feasibility metrics exceeded prespecified benchmarks. Fifty-eight percent of screened patients were eligible, and 69% of eligible patients consented. Of those assigned to MCPC, 93% completed all sessions and 100% of those who completed follow-ups reported using coping skills weekly. Retention was strong at 5-week (85%) and 10-week (78%) follow-ups. Meaning-Centered Pain Coping Skills Training participants reported better scores than control participants across outcome measures, including moderate-to-large sized differences at 10-week follow-up in pain severity (Cohen's d = -0.75 [95% confidence interval: -1.36, -0.14]), pain interference (d = -0.82 [-1.45, -0.20]), and pain self-efficacy (d = 0.74 [0.13, 1.35]).
conclusionsMCPC is a highly feasible, engaging, and promising approach for improving pain management in advanced cancer. Future efficacy testing is warranted.
trial registrationClinicalTrials.gov Identifier: NCT04431830, registered 16 June 2020.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.