SynthesisBMC pregnancy and childbirth2023
Ophthalmic artery Doppler in the complementary diagnosis of preeclampsia: a systematic review and meta-analysis.
Synthesis in BMC pregnancy and childbirth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Towards the Development of a Conceptual Framework of the Determinants of Pre-Eclampsia: A Hierarchical Systematic Review of Biomarkers.BJOG : an international journal of obstetrics and gynaecology · 2026Pooled it
- Added value of ophthalmic artery Doppler in prediction of pre-eclampsia: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Pooled it
- Predictive value of second-trimester ophthalmic artery Doppler for identifying women at risk for preeclampsia.World journal of radiology · 2026Article
- Ophthalmic artery Doppler: reference values in low-risk pregnant women.Archives of gynecology and obstetrics · 2026Article
- Evaluation of Maternal Ophthalmic Artery Doppler Velocimetry at 18 to 24 Weeks of Gestational Age in the Prediction of Preeclampsia.The Indian journal of radiology & imaging · 2026Article
- Ophthalmic artery Doppler and carotid intima-media thickness 3-6 years postpartum in women with and without a history of placental insufficiency.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Cell-free RNAs in maternal peripheral blood as potential biomarkers of preeclampsia: a review.Reproductive biology and endocrinology : RB&E · 2025Review
- Maternal Ophthalmic Artery Resistance in Pregnancies With Pre-Eclampsia Compared to Normotensive Participants.Australasian journal of ultrasound in medicine · 2025Article
- Hemodynamic Insights into Preeclampsia: Comparing Ophthalmic and Uterine Artery Resistive Indices.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Ophthalmic Artery Doppler Indices at 11-13 Weeks of Gestation in Relation to Early and Late Preeclampsia.Journal of clinical medicine · 2025Article
- Relationship of maternal ophthalmic artery Doppler with uterine artery Doppler, hemodynamic indices and gestational age: prospective MATERA study.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Article
- Preliminary exploration of prediction model and nomograph drawing of Doppler peak systolic velocity ratio, peak systolic velocity 1 and peak systolic velocity 2 of ophthalmic artery in pregnant women for small for gestational age infants.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the accuracy of different parameters of the ophthalmic artery Doppler (OAD) in the complementary diagnosis of preeclampsia (PE).
methodsThis meta-analysis adhered to the PRISMA guidelines. To investigate the mean difference in OAD values, peak systolic velocity (PSV), end-diastolic velocity (EDV), second systolic velocity peak (P2), resistance index (RI), pulsatility index (PI), and peak ratio (PR), between PE cases (overall and according to severity) and controls, random-effects meta-analyses were conducted for each Doppler parameter, with overall PE and mild and severe PE subgroups. Diagnostic performance and heterogeneity were evaluated with summary receiver operating characteristic (sROC) curves and 95% confidence intervals obtained with bivariate models.
resultsEight studies stratified the results into mild and severe or late and early PE, involving 1,425 pregnant women. PR and P2 had better diagnostic performance than the other indexes, with the PR of AUsROC at 0.885, the sensitivity of 84%, and specificity of 92%, with a low false-positive rate of 0.08 and the P2 with AUsROC of 0.926, the sensitivity of 85% and specificity of 88%. RI, PI, and EDV showed good performance and consistency across studies but lower AUsROC values of 0.833, 0.794, and 0.772, respectively.
conclusionOphthalmic artery Doppler is a complementary tool with good performance for the diagnosis of overall and severe preeclampsia, with high and best sensitivity and specificity when using PR and P2 parameters.
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