Evidence map›Paper›PMID 37173456›Full record

ArticleCommunications medicine2023

Combined COVID-19 vaccination and hepatitis C virus screening intervention in marginalised populations in Spain.

Jeffrey V Lazarus, Marcela Villota-Rivas, Pablo Ryan, Maria Buti, Lara Grau-López, Guillermo Cuevas, José Luis Espada, William Morón, Raul Felipe Palma-Álvarez, Jordan J Feld and 1 more

Abstract read
In one paragraph

Article in Communications medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jeffrey V LazarusBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain. jeffrey.lazarus@isglobal.org.ORCID http://orcid.org/0000-0001-9618-2299
Marcela Villota-RivasBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0002-7332-735X
Pablo RyanDepartment of Internal Medicine, Hospital Universitario Infanta Leonor, Madrid, Spain.
Maria ButiLiver Unit, Hospital Universitario Vall d'Hebron, Barcelona, Spain.
Lara Grau-LópezDepartment of Psychiatry, Addiction and Dual Diagnosis Section, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Guillermo CuevasDepartment of Internal Medicine, Hospital Universitario Infanta Leonor, Madrid, Spain.
José Luis EspadaHarm reduction Unit "SMASD", Madrid, Spain.
William MorónHarm reduction Unit "SMASD", Madrid, Spain.
Raul Felipe Palma-ÁlvarezDepartment of Psychiatry, Addiction and Dual Diagnosis Section, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Jordan J FeldToronto Centre for Liver Disease, University Health Network, Toronto, Canada.ORCID http://orcid.org/0000-0003-2640-2211
Jorge ValenciaDepartment of Internal Medicine, Hospital Universitario Infanta Leonor, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 has hindered hepatitis C virus (HCV) and HIV screening, particularly in marginalised groups, who have some of the highest rates of these conditions and lowest rates of COVID-19 vaccination. We assessed the acceptability of combining HCV testing with COVID-19 vaccination in a centre for addiction services (CAS) in Barcelona and a mobile testing unit (MTU) in Madrid, Spain.

methodsFrom 28/09/2021 to 30/06/2022, 187 adults from marginalised populations were offered HCV antibody (Ab) testing along with COVID-19 vaccination. If HCV Ab+, they were tested for HCV-RNA. MTU participants were also screened for HIV. HCV-RNA+ and HIV+ participants were offered treatment. Data were analysed descriptively.

resultsFindings show how of the 86 CAS participants: 80 (93%) had been previously vaccinated for COVID-19, of whom 72 (90%) had the full first round schedule; none had a COVID-19 vaccine booster and all received a COVID-19 vaccine; 54 (62.8%) were tested for HCV Ab, of whom 17 (31.5%) were positive, of whom all were tested for HCV-RNA and none were positive. Of the 101 MTU participants: none had been vaccinated for COVID-19 and all received a COVID-19 vaccine; all were tested for HCV Ab and HIV and 15 (14.9%) and 9 (8.9%) were positive, respectively; of those HCV Ab+, 9 (60%) were HCV-RNA+, of whom 8 (88.9%) have started treatment; 5 (55.6%) of those HIV+ had abandoned antiretroviral therapy, of whom 3 (60%) have re-started it.

conclusionsThe intervention was accepted by 54 (62.8%) CAS participants and all MTU participants and can be used in marginalised communities.

Identifiers

PMID37173456
PMCPMC10180614

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.