Evidence map›Paper›PMID 37173277›Full record

SynthesisSchizophrenia bulletin2024

Measures of Social and Occupational Function in Early Psychosis: A Systematic Review and Meta-analysis.

Megan Cowman, Emmet Godfrey, Talissa Walsh, Emma Frawley, David Fowler, Mario Alvarez-Jimenez, Karen O'Connor, Til Wykes, Max Birchwood, Gary Donohoe

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Schizophrenia bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Megan CowmanCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.
Emmet GodfreyCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.
Talissa WalshCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.
Emma FrawleyCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.
David FowlerSchool of Psychology, University of Sussex, Falmer, UK.
Mario Alvarez-JimenezOrygen, Melbourne, Australia.
Karen O'ConnorRISE Early Intervention in Psychosis Service, South Lee Mental Health Service, Cork, Ireland.
Til WykesSchool of Mental Health & Psychological Sciences, King's College London, London, UK.ORCID 0000-0002-5881-8003
Max BirchwoodWarwick Medical School, University of Warwick, Coventry, UK.
Gary DonohoeCentre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, University of Galway, Galway, Ireland.ORCID 0000-0003-3037-7426

Funding

Health Research Board RL-2020-007
6 · The paper itself

Abstract

Deficits in social and occupational function are widely reported in psychosis, yet no one measure of function is currently agreed upon as a gold standard in psychosis research. The aim of this study was to carry out a systematic review and meta-analysis of functioning measures to determine what measures were associated with largest effect sizes when measuring between-group differences, changes over time, or response to treatment. Literature searches were conducted based on PsycINFO and PubMed to identify studies for inclusion. Cross-sectional and longitudinal observational and intervention studies of early psychosis (≤5 years since diagnosis) that included social and occupational functioning as an outcome measure were considered. A series of meta-analyses were conducted to determine effect size differences for between-group differences, changes over time, or response to treatment. Subgroup analyses and meta-regression were carried out to account for variability in study and participant characteristics. One hundred and sixteen studies were included, 46 studies provided data (N = 13 261) relevant to our meta-analysis. Smallest effect sizes for changes in function over time and in response to treatment were observed for global measures, while more specific measures of social and occupational function showed the largest effect sizes. Differences in effect sizes between functioning measures remained significant after variability in study and participant characteristics were accounted for. Findings suggest that more specific measures of social function are better able to detect changes in function over time and in response to treatment.

Indexed as

Psychotic DisordersCross-Sectional StudiesHumansOutcome Assessment, Health Carefunctioning measuresmeasurementpsychosocial functionschizophreniasocial function

Identifiers

PMID37173277
PMCPMC10919778

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.