Evidence map›Paper›PMID 37172725›Full record

ArticleThe Journal of biological chemistry2023

Utilization of dietary mixed-linkage β-glucans by the Firmicute Blautia producta.

Ravindra Pal Singh, Jayashree Niharika, Raksha Thakur, Ben A Wagstaff, Gulshan Kumar, Rikuya Kurata, Dhaval Patel, Colin W Levy, Takatsugu Miyazaki, Robert A Field

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ravindra Pal SinghDepartment of Industrial Biotechnology, Gujarat Biotechnology University, Near Gujarat International Finance Tec (GIFT)-City, Gandhinagar, Gujarat, India; Division of Food and Nutritional Biotechnology, National Agri-Food Biotechnology Institute, SAS Nagar, Punjab, India. Electronic address: ravindra.singh@gbu.edu.in.
Jayashree NiharikaDepartment of Industrial Biotechnology, Gujarat Biotechnology University, Near Gujarat International Finance Tec (GIFT)-City, Gandhinagar, Gujarat, India; Division of Food and Nutritional Biotechnology, National Agri-Food Biotechnology Institute, SAS Nagar, Punjab, India.
Raksha ThakurDivision of Food and Nutritional Biotechnology, National Agri-Food Biotechnology Institute, SAS Nagar, Punjab, India.
Ben A WagstaffDepartment of Chemistry and Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.
Gulshan KumarDivision of Food and Nutritional Biotechnology, National Agri-Food Biotechnology Institute, SAS Nagar, Punjab, India.
Rikuya KurataDepartment of Agriculture, Graduate School of Integrated Science and Technology, Shizuoka University, Shizuoka City, Shizuoka, Japan.
Dhaval PatelDepartment of Industrial Biotechnology, Gujarat Biotechnology University, Near Gujarat International Finance Tec (GIFT)-City, Gandhinagar, Gujarat, India.
Colin W LevyDepartment of Chemistry and Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.
Takatsugu MiyazakiDepartment of Agriculture, Graduate School of Integrated Science and Technology, Shizuoka University, Shizuoka City, Shizuoka, Japan; Research Institute of Green Science and Technology, Shizuoka University, Shizuoka City, Shizuoka, Japan.
Robert A FieldDepartment of Chemistry and Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK. Electronic address: robert.field@manchester.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The β-glucans are structurally varied, naturally occurring components of the cell walls, and storage materials of a variety of plant and microbial species. In the human diet, mixed-linkage glucans [MLG - β-(1,3/4)-glucans] influence the gut microbiome and the host immune system. Although consumed daily, the molecular mechanism by which human gut Gram-positive bacteria utilize MLG largely remains unknown. In this study, we used Blautia producta ATCC 27340 as a model organism to develop an understanding of MLG utilization. B. producta encodes a gene locus comprising a multi-modular cell-anchored endo-glucanase (BpGH16

Indexed as

beta-GlucansDietDietary CarbohydratesEubacterialesGastrointestinal MicrobiomeBifidobacteriumHordeumHumansOligosaccharidesProbioticsbeta-GlucansDietary CarbohydratesOligosaccharidesBlautia productaglucan hydrolaseglucan phosphorylasemetabolismmixed-linkage β-glucan (MLG)

Identifiers

PMID37172725
PMCPMC10318527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.