Evidence map›Paper›PMID 37172509›Full record

ArticleJournal of psychiatric research2023

Differing associations of depersonalization with physiological response during rest and breath-focused mindfulness in a trauma-exposed female population.

Emma C Lathan, Alfonsina Guelfo, Dominique L La Barrie, Andrew Teer, Abigail Powers, Greg Siegle, Negar Fani

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Racial Discrimination-Related Interoceptive Network Disruptions: A Pathway to Disconnection.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Emma C LathanDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: elathan@emory.edu.
Alfonsina GuelfoDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: aguelfo@emory.edu.
Dominique L La BarrieDepartment of Psychology, University of Georgia, Athens, GA, USA. Electronic address: dominiquelabarrie@gmail.com.
Andrew TeerHome Base, a Red Sox Foundation and Massachusetts General Hospital Program, Massachusetts General Hospital, Charlestown, MA, USA; Department of Psychiatry, Harvard Medical School, Cambridge, MA, USA. Electronic address: ateer@mgh.harvard.edu.
Abigail PowersDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: Abigail.lott@emoryhealthcare.org.
Greg SiegleDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: gsiegle@pitt.edu.
Negar FaniDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA. Electronic address: nfani@emory.edu.
Emory University · USHarvard University · USUniversity of Georgia · USUniversity of Pittsburgh · US

Funding

Neural Mechanisms of Vibroacoustically Augmented Breath Focused Mindfulness for Dissociative Traumatized PeopleR01AT011267 · NCCIH · EMORY UNIVERSITY · PI FANI, NEGAR, SIEGLE, GREG J · 2021 to 2025
$4.1M
Neural Mechanisms of Cognitive Control in Posttraumatic Stress DisorderK23MH101380 · NIMH · EMORY UNIVERSITY · PI FANI, NEGAR · 2014 to 2017
$601k
NCCIH NIH HHS R01 AT011267NIMH NIH HHS K23 MH101380
6 · The paper itself

Abstract

backgroundDissociative and posttraumatic stress disorder (PTSD) symptoms are commonly co-occurring responses to psychological trauma. Yet, these two groups of symptoms appear to be related to diverging patterns of physiological response. To date, few studies have examined how specific dissociative symptoms, namely, depersonalization and derealization, relate to skin conductance response (SCR), a marker of autonomic function, within the context of PTSD symptoms. We examined associations among depersonalization, derealization, and SCR during two conditions - resting control and breath-focused mindfulness - in the context of current PTSD symptoms.

methodsSixty-eight trauma-exposed women (82.4% Black; M

resultsModeration analyses revealed that depersonalization was linked to lower SCR during resting control, B = 0.0005, SE = 0.0002, p = .006, in participants low-to-moderate PTSD symptoms; however, depersonalization was associated with higher SCR during breath-focused mindfulness, B = -0.0006, SE = 0.0003, p = .029, in individuals with similar levels of PTSD symptoms. No significant interaction between derealization and PTSD symptoms on SCR was observed.

conclusionsDepersonalization symptoms may associate with physiological withdrawal during rest, but greater physiological arousal during effortful emotion regulation in individuals with low-to moderate levels of PTSD, which has significant implications for barriers to treatment engagement as well as treatment selection in this population.

Indexed as

MindfulnessPsychological TraumaStress Disorders, Post-TraumaticAdultChildDepersonalizationDissociative DisordersFemaleHumansDepersonalizationDerealizationDissociationPosttraumatic stress disorderSkin conductanceTrauma exposure

Identifiers

PMID37172509
PMCPMC10305839
OpenAlexW4372199738

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.