Evidence map›Paper›PMID 37172265›Full record

ReviewHuman reproduction (Oxford, England)2023

Trauma and female reproductive health across the lifecourse: motivating a research agenda for the future of women's health.

Alexandra Hillcoat, Jaya Prakash, Leah Martin, Yu Zhang, Gabriela Rosa, Henning Tiemeier, Nicole Torres, Vicente Mustieles, Charleen D Adams, Carmen Messerlian

Open access · greenAbstract readReview
In one paragraph

Review in Human reproduction (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Alexandra HillcoatDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Jaya PrakashDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Leah MartinDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Yu ZhangDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Gabriela RosaOffice of Educational Programs, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Henning TiemeierDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-4395-1397
Nicole TorresDepartment of Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital Fertility Center, Boston, MA, USA.
Vicente MustielesDepartment of Radiology and Physical Medicine, School of Medicine, Center for Biomedical Research (CIBM), University of Granada, Granada, Spain.ORCID 0000-0002-2010-5438
Charleen D AdamsDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Carmen MesserlianDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-3884-1492
Harvard University · USMassachusetts General Hospital · USOffice of Education · USUniversidad de Granada · ES

Funding

Training Program in Molecular and Integrative Physiological SciencesT32HL007118 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LU, QUAN · 1985 to 2025
$14.3M
The Impact of Maternal and Paternal Preconception Perfluoroalkyl Substance (PFAS) Exposure on Reproductive and Perinatal OutcomesR01ES031657 · NIEHS · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI MAHALINGAIAH, SHRUTHI · 2020 to 2024
$3.1M
NHLBI NIH HHS T32 HL007118NIEHS NIH HHS R01 ES031657
6 · The paper itself

Abstract

The aetiology behind many female reproductive disorders is poorly studied and incompletely understood despite the prevalence of such conditions and substantial burden they impose on women's lives. In light of evidence demonstrating a higher incidence of trauma exposure in women with many such disorders, we present a set of interlinked working hypotheses proposing relationships between traumatic events and reproductive and mental health that can define a research agenda to better understand reproductive outcomes from a trauma-informed perspective across the lifecourse. Additionally, we note the potential for racism to act as a traumatic experience, highlight the importance of considering the interaction between mental and reproductive health concerns, and propose several neuroendocrinological mechanisms by which traumatic experiences might increase the risk of adverse health outcomes in these domains. Finally, we emphasize the need for future primary research investigating the proposed pathways between traumatic experiences and adverse female reproductive outcomes.

Indexed as

Psychological TraumaReproductive HealthWomen's HealthBiomedical ResearchFemaleForecastingHumansLife Change EventsMental Healthfemale reproductive healthinfertilitylifecoursemental healthpregnancy complicationspremenstrual dysphoric disorderstresstrauma

Identifiers

PMID37172265
PMCPMC10391316
OpenAlexW4376270185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.