Evidence map›Paper›PMID 37171750›Full record

ArticleCell stress & chaperones2023

Cellular protection from H

Chris Hino, Grace Chan, Gwen Jordaan, Sophia S Chang, Jacquelyn T Saunders, Mohammad T Bashir, James E Hansen, Joseph Gera, Richard H Weisbart, Robert N Nishimura

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell stress & chaperones, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Chris HinoDept. of Internal Medicine, Loma Linda School of Medicine, Loma Linda, CA, 92350, USA.
Grace ChanVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
Gwen JordaanVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
Sophia S ChangVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
Jacquelyn T SaundersVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
Mohammad T BashirVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
James E HansenVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
Joseph GeraVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
Richard H WeisbartVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA.
Robert N NishimuraVA Greater Los Angeles Healthcare System, North Hills, Los Angeles, CA, 91343, USA. rnishimu@g.ucla.edu.ORCID 0000-0003-2041-9135
University of California, Los Angeles · USVA Greater Los Angeles Healthcare System · USLoma Linda University · USYale University · US

Funding

Co-targeting mTOR and YAP signaling in glioblastomaR01CA217820 · NCI · GREATER LOS ANGELES VETERANS RESEARCH AND EDUCATION FOUNDATION · PI GERA, JOSEPH F · 2018 to 2022
$1.6M
NCI NIH HHS R01 CA217820
6 · The paper itself

Abstract

Heat shock proteins (HSPs), especially Hsp70 (HSPA1), have been associated with cellular protection from various cellular stresses including heat, hypoxia-ischemia, neurodegeneration, toxins, and trauma. Endogenous HSPs are often synthesized in direct response to these stresses but in many situations are inadequate in protecting cells. The present study addresses the transduction of Hsp70 into cells providing protection from acute oxidative stress by H

Indexed as

Hydrogen PeroxideNeuroblastomaAdenosine TriphosphatasesCatalaseCysteine SynthaseHeat-Shock ProteinsHSP70 Heat-Shock ProteinsHumansRecombinant ProteinsAdenosine TriphosphatasesCatalaseCysteine SynthaseHeat-Shock ProteinsHSP70 Heat-Shock ProteinsHydrogen PeroxideRecombinant ProteinsCatalaseGamma-glutamyl-cysteine synthaseHeme oxygenase-1Hsp70Nrf 2Oxidative cell death

Identifiers

PMID37171750
PMCPMC10352194
OpenAlexW4376226281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.