SynthesisCJEM2023
Inhaled nitrous oxide for painful procedures in children and youth: a systematic review and meta-analysis.
Synthesis in CJEM, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Recreational nitrous oxide-related myeloneuropathy in adolescents: a multicenter retrospective case series and systematic literature review.European journal of pediatrics · 2026Pooled it
- Pooled it
- Article
- Intranasal and Oral Pharmacological Sedation in Pediatric Dentistry: A Thematic Scoping Review of Efficacy, Recovery, and Safety Outcomes.Children (Basel, Switzerland) · 2026Review
- Analyzing the Efficacy and Potential Risks of Nitrous Oxide for Pain Management During Labor: A Narrative Review.Clinical pharmacology : advances and applications · 2026Review
- Pediatric procedural sedation and analgesia in the emergency setting in community hospitals in Italy: current status and challenges.Italian journal of pediatrics · 2025Article
- The consensus statement of the Section of Paediatric Anaesthesiology and Intensive Therapy of the Polish Society of Anaesthesiology and Intensive Therapy on anaesthesia in children over 3 years of age.Anaesthesiology intensive therapy · 2025Article
- Analgesic effect of premixed nitrous oxide/oxygen on removal of vacuum assisted closure dressings: randomized controlled trial study protocol.Journal of orthopaedic surgery and research · 2025Article
- Article
- Anxiolysis for laceration repair in children: study protocol for an open-label multicenter adaptive trial (ALICE).PloS one · 2025Article
- Administration of Nitrous Oxide by Medical Assistants for Painful Procedures in Outpatient Pediatric Settings.Children (Basel, Switzerland) · 2024Article
- We can do better for children in distress.CJEM · 2024Article
- Article
- Pain Management in Children Admitted to the Emergency Room: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objective of this study was to synthesize indication-based evidence for N STUDY
designWe included trials of N
resultsWe included 30 trials. For pain using the Visual Analog Scale (0-100 mm) during IV insertion, 70% N
conclusionsThere is sufficient evidence to recommend N
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.