Evidence map›Paper›PMID 37171515›Full record

ArticleInternational orthopaedics2023

Bone allografting: an original method for biological osteosynthesis and bone reinforcement in children with osteogenesis imperfecta.

Mathilde Gaume, Sarah El Yahiaouni, Marine De Tienda, Genevieve Baujat, Valérie Cormier-Daire, Valérie Dumaine, Stéphanie Pannier, Georges Finidori, Zagorka Pejin

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In one paragraph

Article in International orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mathilde GaumeDepartment of Pediatric Orthopaedics Surgery, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, 149 rue de Sèvres, 75015, Paris, France. mathilde.gaume@hotmail.fr.
Sarah El YahiaouniDepartment of Pediatric Orthopaedics Surgery, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, 149 rue de Sèvres, 75015, Paris, France.
Marine De TiendaDepartment of Pediatric Orthopaedics Surgery, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, 149 rue de Sèvres, 75015, Paris, France.
Genevieve BaujatDepartment of Pediatric Genetics, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, Paris, France.
Valérie Cormier-DaireDepartment of Pediatric Genetics, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, Paris, France.
Valérie DumaineDepartment of Orthopaedics Surgery, Cochin Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, Paris, France.
Stéphanie PannierDepartment of Pediatric Orthopaedics Surgery, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, 149 rue de Sèvres, 75015, Paris, France.
Georges FinidoriDepartment of Pediatric Orthopaedics Surgery, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, 149 rue de Sèvres, 75015, Paris, France.
Zagorka PejinDepartment of Pediatric Orthopaedics Surgery, Necker Hospital, Assistance Publique Hopitaux de Paris, Université Paris-Cité, 149 rue de Sèvres, 75015, Paris, France.
Université Paris Cité · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOsteogenesis imperfecta (OI) is a genetic disorder responsible for various symptoms including deformities and frequent fractures. Bone allografting is poorly documented in this condition. The objective of this study was to describe our experience and assessments in a consecutive series of OI patients.

methodsThirty-nine lower limb allograft procedures (28 femurs, 11 tibias) were performed in 26OI patients (mean age, 12.9 years). They were classified as type III of Sillence (17), type IV (6), and 3 recessive forms. The indications for surgery were correction of deformity (19), fracture (16), and non-union (4). In all cases, bone allografting was added to reinforce areas of fragility and in 28 cases for osteosynthesis to lock the rotations at the osteotomy site and to avoid screwed metallic plate. The duration of bone consolidation and allograft fusion was assessed. Complications and Gillette functional score were reported.

resultsThe mean follow-up was 6.7years (range, 2 to 10 years). On average, bone consolidation was achieved after 3.3 months and graft fusion after 7.7 months. No bone allograft-related complications were observed and there was any secondary displacement. The Gillette functional score was improved in 23 patients and stable in three cases. Complications were reported in two cases: one partial allograft resorption and one delayed consolidation of a non-union. One refracture was observed but after a significant trauma in a child who had regained significant physical activity.

conclusionsBone allografting in children with OI is a reliable method of biological fixation, allowing efficient fusion and contributing to increased bone capital and functional outcome.

Indexed as

Fractures, BoneOsteogenesis ImperfectaChildFemurFracture Fixation, InternalHumansTransplantation, HomologousBiological bone fixationBone allograftBone osteosynthesisOsteogenesis imperfectaStructural bone graftSupplemental fixation

Identifiers

PMID37171515
OpenAlexW4376226669

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.