Evidence map›Paper›PMID 37171492›Full record

ArticleEuropean radiology2023

Atypical primary central nervous system lymphoma and glioblastoma: multiparametric differentiation based on non-enhancing volume, apparent diffusion coefficient, and arterial spin labeling.

Xiaojun Yu, Weiping Hong, Minting Ye, Mingyao Lai, Changzheng Shi, Linzhen Li, Kunlin Ye, Jiali Xu, Ruyu Ai, Changguo Shan and 2 more

Abstract read
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Microstructure mapping with time-dependent diffusion MRI differentiates primary central nervous system lymphoma from glioblastoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Xiaojun Yu *Medical Imaging Center, The First Affiliated Hospital of Jinan University, No. 613, Huangpu Road West, Tianhe District, Guangdong Province, Guangzhou, 510630, China.
Weiping Hong *Department of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, 510510, China.
Minting YeDepartment of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, 510510, China.
Mingyao LaiDepartment of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, 510510, China.
Changzheng ShiMedical Imaging Center, The First Affiliated Hospital of Jinan University, No. 613, Huangpu Road West, Tianhe District, Guangdong Province, Guangzhou, 510630, China.
Linzhen LiMedical Imaging Center, The First Affiliated Hospital of Jinan University, No. 613, Huangpu Road West, Tianhe District, Guangdong Province, Guangzhou, 510630, China.
Kunlin YeMedical Imaging Center, The First Affiliated Hospital of Jinan University, No. 613, Huangpu Road West, Tianhe District, Guangdong Province, Guangzhou, 510630, China.
Jiali XuMedical Imaging Center, The First Affiliated Hospital of Jinan University, No. 613, Huangpu Road West, Tianhe District, Guangdong Province, Guangzhou, 510630, China.
Ruyu AiDepartment of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, 510510, China.
Changguo ShanDepartment of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, 510510, China.
Linbo CaiDepartment of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou, 510510, China. cailinbo999@163.com.
Liangping LuoMedical Imaging Center, The First Affiliated Hospital of Jinan University, No. 613, Huangpu Road West, Tianhe District, Guangdong Province, Guangzhou, 510630, China. tluolp@jnu.edu.cn.

Funding

Guangzhou Key Laboratory of Molecular and Functional Imaging for Clinical Translation 201905010003
6 · The paper itself

Abstract

objectivesTo evaluate the multiparametric diagnostic performance with non-enhancing tumor volume, apparent diffusion coefficient (ADC), and arterial spin labeling (ASL) to differentiate between atypical primary central nervous system lymphoma (PCNSL) and glioblastoma (GBM).

methodsOne hundred and fifty-eight patients with pathologically confirmed typical PCNSL (n = 59), atypical PCNSL (hemorrhage, necrosis, or heterogeneous contrast enhancement, n = 29), and GBM (n = 70) were selected. Relative minimum ADC (rADC

resultsAtypical PCNSLs showed significantly lower rADC

conclusionThe combined evaluation of rADC KEY POINTS: • Atypical PCNSL is easily misdiagnosed as glioblastoma, which leads to unnecessary surgical resection. • The nET volume, ADC, and ASL-derived parameter (CBF) were lower for atypical PCNSL than that for glioblastoma. • The combination of multiple parameters performed well (AUC = 0.96) in the discrimination between atypical PCNSL and glioblastoma.

Indexed as

Brain NeoplasmsGlioblastomaLymphomaCentral Nervous SystemDiagnosis, DifferentialHumansMagnetic Resonance ImagingSpin LabelsSpin LabelsCentral nervous systemGlioblastomaLymphomaMagnetic resonance imagingTumor volume

Identifiers

PMID37171492
PMCPMC10326108

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.